Getting buff without the sweat is cheating

treadmill — Thu, 07 Aug 2008 13:01:51 GMT

Fitness pills - that's just stupid

Getting buff without the sweat is cheating

Nick, Salt Lake City, UT — Thu, 07 Aug 2008 13:41:23 GMT

This drug could improve and potentially save millions of lives. I'm all for it. Imagine combining this drug with diet and exercise... the results would be amazing.

Getting buff without the sweat is cheating

Paul — Thu, 07 Aug 2008 13:47:35 GMT

I am 53 and my joints ache all the time. I take vicodin regularly to relieve the pain. I feel miserable because I do not exercise like I should. It hurts to ride a stationary bike or walk for any length of time that would help me out aerobically. When I was younger I was in great shape. If these pills were available I would be the first to try them!

Getting buff without the sweat is cheating

Jim M. Freeport Maine — Thu, 07 Aug 2008 13:50:38 GMT

Bring on the Aicar....I'll give it a few years first to make sure the first round of folks don't spontaneously combust.

The reality will likely be a mix of exercise and some GW1516. There's no going back on these kinds of drugs now that the genie is out of the box. If true, they'll become too important to a lazy and fat society like our own. The implications for our health care system (with positive benefits) is too much to ignore.

Getting buff without the sweat is cheating

Dorothy Reames, Fort Mill, SC — Thu, 07 Aug 2008 14:09:36 GMT

I pray for something, even in the form of a pill that will help my 12 year old son be able to scratch his own nose or turn his own head, or breathe without a ventilator pushing every breath since the day he was born into his lungs--instead of just watching a muscle wasting disease slowly, cruely, either take him from us or day by day make him just waste away. Some may think there's not many that would benefit from a heath stance, bet you'd be surprised.

Getting buff without the sweat is cheating

E. Bradstreet, Winter Park, FL — Thu, 07 Aug 2008 14:15:04 GMT

I was in the Army, I had to exercise every day for years, and I never found 'the act' of pumping iron or running to be enjoyable. What I did enjoy, was feeling strong, and being able to accomplish every day activities without noticeable effort.

If they can show me that this works, and if they can keep the price down, I'll take it.

Getting buff without the sweat is cheating

Djinn , Chicago — Thu, 07 Aug 2008 14:18:03 GMT

It sounds good for those with time constrainents. Also for those to ill to work out .
Questions would be what are the side effects of the drug , long term benefits and/or harms.
Cost and availability are questions also.

Getting buff without the sweat is cheating

Todd, StL, MO — Thu, 07 Aug 2008 14:18:11 GMT

A pill would be great. Exercise has become a job unto itself. You have to actually make time to go somewhere else to spend an hour or so running in place or whatever to be healthy and it's oh so easy to give in to laziness and miss a day or seven at a time. Other than sleep I only get a few hours at home a day after you figure in the commute time back and forth to work.

It'd be nice to think that I was able to maintain my body at a certain healthy level so when I asked it to do something it wouldn't complain about doing it. I think a pill that helped keep me in better shape would make me want to use my body more and be more active...

Getting buff without the sweat is cheating

Curtis Rogers, St. Louis, MO — Thu, 07 Aug 2008 14:23:48 GMT

Actually, for someone suffering from a muscular dystrophy and unable to workout or even exercise a drug that can help me stay in shape would be a Godsend, even help prolong my life. Aren't the so called "miracle drugs" supposed to offer people like me a small glimmer of hope, maybe improve my quality of life? Would it really be "cheating" for someone like me to take a drug like this? Just because some muscle bound neanderthal, that takes walking for granted, thinks this is horrible, is it really so horrible for the millions of people that have MD or similar ailments? I went to college on an athletic scholarship and now I walk with a cane (I'm only 38 too). Soon I'll be in a wheel chair because of the muscle loss so why wouldn't a drug like this be just what the Dr. ordered?
If you're looking for someone in human trials, I'll be the first to sign up. Why should I be denied the same quality of life as everyone else?

Getting buff without the sweat is cheating

Craig, Houston, Texas — Thu, 07 Aug 2008 14:26:13 GMT

Well I, for one, am interested in this pill. Most beneficial exercise results in sweating. However, for those of us with AP (aquagenic pruritus), sweating is a bad thing. In fact, any contact with water is bad. If you think this is funny, imagine back to one of your really bad sunburns or perhaps you received a burn from a fire or stove. Do you remember how badly that hurt. Now imagine having that feeling over 80 to 90% of your body everytime you sweat, or shower, or get caught out in the rain. The idiot who said "A little rain never hurt anyone" didn't know someone with AP. I know I need to exercise my body and I need to loose a little weight, but I can't exercise to the point of getting sweaty. What would you wish for if you were in my situation? Check it out, there are several thousand of us with this condition all over the world. We would like to be recognized at some point about our condition. Many doctors don't appreciate the pain we endure.

Getting buff without the sweat is cheating

Mike J, St. Louis, MO — Thu, 07 Aug 2008 14:29:59 GMT

I know people suffering from muscle diseases that would line up for something like this. Why should some people be denied the same rights to a decent quality of life as everyone else solely because it comes in pill form? My best friend can't walk up or down stairs, for him, this could save his life.

Getting buff without the sweat is cheating

Allen McCready, Pittsburgh, PA — Thu, 07 Aug 2008 14:37:14 GMT

Hey...if God wanted man to fly, God would have given man wings. Wait...he did. He gave man a brain and an opposing thumb with which to build wings. If God wanted man to wear clothes, he would have given him clothes. Etc.

For those who enjoy working out just to work out, there is nothing to prevent them from still doing so, just as there is nothing to prevent people who earn big bucks from also enjoying just looking at those big bucks as well.

I think those who will feel most cheated by such inventions are those born with the results already in place, or the time to make the improvements, or the money, etc. Their edge over others will be but momentary and such edges are not yielded easily.

(Many of my past comments have never been published. It will be interesting to see if this one makes it. Perhaps there is a pill...)

Getting buff without the sweat is cheating

Dave,Sacramento,Ca — Thu, 07 Aug 2008 14:45:12 GMT

Um, isn't this a PERFORMANCE ENHANCING DRUG??? The hypocrisy

Getting buff without the sweat is cheating

Mitch NY NY — Thu, 07 Aug 2008 14:49:25 GMT

The reward from dedicating yourself to regular exercise is far greater than just in the calories burned in a session. You gain a sense of "I can do this" that you apply to all aspects of your personal and professional life.

A pill will never replicate this. You might get thinner on the outside but you can never escape who you are on the inside.

Getting buff without the sweat is cheating

Sam Iredale — Thu, 07 Aug 2008 14:56:36 GMT

This isn't going to be able to entirely replace exercise. This may help trim the fat and grow lean muscle mass; but people who rely to heavy on devices like this (and steroids) won't develop all of the strengths they think they are.

For example, one of the problems that steroid users face is that of over-developed musculature on a not as developed skeletal frame. Ligaments aren't developed enough to support the muscle strength; and injuries ensue. I suspect in this case, there would be a similar problem. Skeletal and ligament strength would need to be developed to support the musculature.

Aside from that, I think for people who aren't competing in professional sports (and have no plans of ever doing so) would do well to use any and every tool available to them to develop and maintain their health. To that end, in this day of busy schedules where exercise is largly becoming more of a luxury, I'm all for it!

But there are no short cuts.

For the record, for exercise, I study Kung Fu at the Seattle Kung Fu club three times a week, with some weight training and extra cardio in my off days. I plan to compete in amature tournaments, and will probably never use this pill or anything like it.

Getting buff without the sweat is cheating

Sandy, Dayton, oH — Thu, 07 Aug 2008 14:59:18 GMT

God loves the Scientist, too. Go exercise pill. To all of you masochistic iron pumpers, oh wahhhh!

Getting buff without the sweat is cheating

bridget newport news, va — Thu, 07 Aug 2008 15:00:29 GMT

I can see the upsides of a drug like this for those who are ill or physically incapable of exercise. But for the millions of overweight Americans who have no desire to keep themselves healthy because it is too much work and they would rather eat junk, then this is a bandaid, because it will not change their eating habits or make them take better care of themselves. I don't like getting up at 5:30 and going to the gym, but I do know to get my butt off the couch when my pants start to get too tight!

Getting buff without the sweat is cheating

John Henderson Austin, TX — Thu, 07 Aug 2008 15:01:48 GMT

I can't believe that a doctor would tout the wonders of hard heavy exercise in the gym while completely disregarding the fact that there are severe negative effects as well. The positives (increased cardio-vascular health, etc) do vastly outweigh the negatives (the high percentage of joint injuries to knees, hips and back as well as the connective tissue injuries to ligaments, etc), so currently it is better, much better overall, to exercise than to not exercise. There is no doubt about that.

However, a vast majority of the downside of exercise takes place during the 'build-up' to fitness when people are out of shape and pushing themselves to extremes to get visual results, not once they are fit (the exception being those people that continue to exercise very hard for the sake of exercising very hard and not for actual overall fitness benefits).

These pills might allow the couch-potato generation to reach a moderate level of fitness without permanently damaging themselves. They could then go on to finish the transition to fitness in the gym, thereby getting all of the positive aspects of exercise without incurring much, if any, of the negatives.

Getting buff without the sweat is cheating

ND, Pittsburgh, PA — Thu, 07 Aug 2008 15:12:52 GMT

I would really be interested to see if it could help to enhance the current exercise routine of someone like me. I regularly exercise but never seem to "bulk up" at all. It would be nice to get some help with my exercise routine without having to exercise to the point of exhaustion.

Getting buff without the sweat is cheating

Brian S. Racine, WI — Thu, 07 Aug 2008 15:13:20 GMT

I'm a well built bodybuilder that takes great pride in working out harder than the next guy and having such a pill is taking a FAT, LAZY, and DISGUSTINGLY OVERWEIGHT american society and making them even worse.....if someone wants to get in shape they should do what it takes not take a pill.....

Getting buff without the sweat is cheating

Stephen, Wheaton, Illinois — Thu, 07 Aug 2008 15:18:57 GMT

If getting in shape through drugs was a good idea, why didn't God incorporate that in our design instead of multiple, superimposed control systems which, btw, tend to reconfigure and/or adapt under outside influences?

Getting buff without the sweat is cheating

Caitlin, Austin, TX — Thu, 07 Aug 2008 15:24:03 GMT

UM... AWESOME... and I agree with nick, combine it with regular exercise and you'll get twice if not 3 times the benefits! I'd try it... after other people try it... you never know what kind of adverse effects it could have...

Getting buff without the sweat is cheating

MReckless — Thu, 07 Aug 2008 15:26:29 GMT

I work all day long and get tired easily and dont have time to go to the Gym... I would love to try this. I think it would be great for people chained to couches who weigh more than they can carry, for children who need help, and for people who work long hours like me. Now I want to try this...

Getting buff without the sweat is cheating

Mike, St. Louis — Thu, 07 Aug 2008 15:30:24 GMT

I've a problem with the author and her significant other's vanity and smug superiority. In particular, when she says, "Our poignant determination to remain vital and sexually attractive and dignified in the face of looming mortality really is life itself." Nice to see a human being is to be judged on shear physical criteria.

As a species, we are not particuarly strong, fast, agile, etc. It's an illusion to define one's "superiority" in such terms or it as "life itself." Many can have the body of Adonis is they put the work in to it, yes, but at what price? How much self-absorbtion does it take to spend that much time sculpting ones body? How does one look and judge the value of others in comparison if the criteria is materialistic is nature? And if nature is more capricious to some than others, do they lose their value because they are no longer able to reach the pinncale of physical perfection? I think perhpas she and the Leyner should consider the consequences and ramifications of such a train of thought.

From my perspective, the value of a human being is not defined so crassly as "who's the hottest, buffest person around." That is not the meaning of life or even a criteria to judge ones value on. Some cannot exercise as much as others due to physical ailments, time constraints and obligations, or simply because they are not so self-consumed to worry about transitory health and beauty at the expense of more vital matters. So, if a pill could help many who cannot devote the time or lack the physical (or economic) resources, I see no problem with it. That's what ultimately sets humans apart, after all: Our ability to understand and modify our world not only for our own benefit, but for others as well, even when it might mean giving up an advantage some have over others (such as having the time and resources to devote to excessive exercise).

Getting buff without the sweat is cheating

Luke, Columbus, Ohio — Thu, 07 Aug 2008 15:35:28 GMT

The problem that I am having is that, the article says it helps grow Type 1 fibers, what does it do to the tendons and other connective tissue? Does it help those too? I mean it would not be fun to have powerful muscles that would shred everything that they are connected too.

Getting buff without the sweat is cheating

MM,NY,NY — Thu, 07 Aug 2008 15:37:57 GMT

Now if they can just invent a smart pill.....

Getting buff without the sweat is cheating

Hamlet Lexington, KY — Thu, 07 Aug 2008 15:39:51 GMT

Sooo, if we can get a fitnesss pill, why can't we have Phen-Fen? Compared to "male enhancement" medication, the risks are infintesimal, but because women made up 96% of users, it was taken off the market. Why doesn't some woman scientist find out exactly the percentage of males who have had heart attacks from taking male enhancement drugs? I bet we'd all be surprised. That's not going to happen, though IS IT?????

Getting buff without the sweat is cheating

pat, douglasville, ga — Thu, 07 Aug 2008 15:40:39 GMT

i am 55 years old. every move i make hurts. i have just moved to a new house and arranged, packed, lugged, painted, repaired - everything myself and my legs and knees and hands are still hurting weeks later. if there is a pill that can help me lose weight so that i can do all of these things and more without the pain - i am all for it. since the writers of this article are both men - sell only to women!

Getting buff without the sweat is cheating

Mike Davis — Thu, 07 Aug 2008 15:43:17 GMT

All AICAR and related drugs do is make it easier to burn energy, but you still need to do SOMETHING to burn it. If you need to get rid of 2000 calories, you will still need to do 2000 calories of exercise to get rid of it.

Getting buff without the sweat is cheating

Bill MC, Jax FL — Thu, 07 Aug 2008 15:48:59 GMT

Good point Todd. I have recently, (almost 3 mths) taken up working out at least twice a week and while my workouts are no more than 20 - 30 mins at a time there is nothing enjoyable about working out other than the end result. It is a job unto itself. However this is the price we "pay" in order to be in good health so that we can be active. PASS, give me an affordable miracle pill with limited to no side effects and I will take it daily right along with my vitamin supplement.

Getting buff without the sweat is cheating

Ray — Thu, 07 Aug 2008 15:54:11 GMT

I work 10-12 hours a day at a desk. Then I go home and try to be a father to 4 kids. Being able to be more "there" for them would definately be very inviting. As another writer mentioned, give it a couple of years to make sure users don't spontaneously combust and I'm in.

Getting buff without the sweat is cheating

Jen R. Des Moines IA — Thu, 07 Aug 2008 15:59:00 GMT

This just shows society's NEED for instant gratification. No one wants to take time and put in effort to be healthy, they just want to pop a pill, close their eyes, and their dream body will suddenly appear. Though these drugs would be beneficial for a SMALL percentage of people, they will ultimately be used by those that want to sit on the butts and not put in the effort. Its a wonder why there is an obesity epidemic in this country...

Getting buff without the sweat is cheating

Such a Bastard — Thu, 07 Aug 2008 16:05:21 GMT

Great. Instead of a bunch of fat asses sitting in front of their computers all day and night munching on chips and drinking sodas while playing World of Warcraft and wasting their lives, there'll be a bunch of skinny hot sexy people doing it! I don't play those games, but, hell, sign me up for those pills!

Getting buff without the sweat is cheating

Jirby, Colorado Springs, CO — Thu, 07 Aug 2008 16:07:03 GMT

Now that obesity is a disease that has come to plague all developing nations, it will be considered a Godsend like Viagra. Each year, 438,000 people die from the effects of nicotine. The COPD that smoking brings on makes exercise vital to extending life by two or three years. To sufferers of COPD, aerobic exercise can be torture, and the more obese you become, the more difficult exercise is. And the more likely type 2 diabetes is to set in. We really need something like this, and the sooner the better.

Getting buff without the sweat is cheating

Jerry, Albuquerque, NM — Thu, 07 Aug 2008 16:09:21 GMT

You young kids! When I was your age, I had to walk to school...in the snow...uphill...both ways!

Come on, grow up. If it works for people, we end up with a healthier population. Endorphine junkies will still go to the gym. No, the real question is what the side effects will be, and will anyone in the US, or indeed, the world, be able to afford it if it does work.

Getting buff without the sweat is cheating

Monson, Ma — Thu, 07 Aug 2008 16:12:16 GMT

I'd like to buy some exercise in a pill today. Where can I get this?

Getting buff without the sweat is cheating

jp,sc — Thu, 07 Aug 2008 16:16:41 GMT

when it is going available

Getting buff without the sweat is cheating

Joe, Jacksonville, FL — Thu, 07 Aug 2008 16:26:15 GMT

I agree with "Paul". I'm 56 and have always fought the battle of the bulge. I still count calories and fat content. When young and in the military, control was easier but still a battle. Once out of that lifestyle and a life of hard work, I don't have a joint that doen't hurt. Being overweight and out of shape is not pleasent but neither is trying to run on a treadmill or even a decent walk. If this pill can help get the weight down and boost muscle, that alone will help the joints. If that ocurrs a combination of exercise and a resonable diet will go a long way to improving my lifestyle.

Getting buff without the sweat is cheating

Joseph Dog, San Diego, CA — Thu, 07 Aug 2008 16:27:03 GMT

Cheating? So is having sex without the risk of pregnancy. Condoms and birth control pills/shots are not natural, so we should do away with it all, right?

Getting buff without the sweat is cheating

Lee, TX — Thu, 07 Aug 2008 16:27:17 GMT

Muscle mass alone won't burn enough fat to overcome a couch potato.

Sure they'd have more muscle mass, but they'd still have pounds of fat on top.

It won't change your attitude about work (work = physical output), but it can help some people overcome some hurdles.

IE. I can't benchpress, because I can't balance the bar.
Some machines have the settings too far apart, setting 1 does me nothing, 2 is too difficult.
Recovery. I broke my legs and couldn't walk for weeks, how do I maintain the muscle mass?

Recovery from space station trips. Usually they lose an unhealthy amount of muscle mass. This is probably one of the drives for this pill.

I doubt this will ever be non-prescription.

Getting buff without the sweat is cheating

Tori Charlotte NC — Thu, 07 Aug 2008 16:27:31 GMT

Then call me a cheater! It looks to me like this pill would be a great method of starting an exercise program. Don't most of us quit because it is too hard, because we don't like it, etc? What if our body exercised easily and without the soreness etc from the first day we tried it? Seems to me we might actually stick with it and shed that diabetes and heart disease inducing poundage. Just a thought...

Getting buff without the sweat is cheating

Garrett, Troy NY — Thu, 07 Aug 2008 16:30:34 GMT

Honestly I think a drug of this nature would cause more harm than good if it were offered to the general population and not exclusively used to treat illnesses. What would be the point of any sport if you didn't have to train or work hard to become good at it?

If you choose a career that requires you to work 80 hours a week then that is your choice of how to spend your time. Most people don't realize that it really doesn't take that much time or effort to stay in decent shape. The problem is the effort...people want to look like professional athletes and supermodels without having to do anything. If you want that level of fitness then you have to pay the price of putting in the time and effort.

As this article mentions, building muscle and having a fit body are not all of the benefits of exercise. Many of the benefits of exercise are due to the chemicals your body produces during it. If you take a pill for exercise you won't be producing these and you'll still be someone that's depressed, who happens to be in shape....

Getting buff without the sweat is cheating

Matt, Den, CO — Thu, 07 Aug 2008 16:32:07 GMT

I think that this article is taking it to the extreme that everyone would become Adonis-like. It would be very beneficial for those who are overweight, self included, to finally get out of the red zone for diabetes and heart conditions, and be able to still put the hours of exercise that would have taken into our work and families.

Getting buff without the sweat is cheating

Deborah Shupe, Chester Springs, PA — Thu, 07 Aug 2008 16:33:16 GMT

I had a back injury just over a year ago. I've had surgery, epidural injections and MANY tests. Nothing has helped me with the pain and inability to walk on my own. My whole body has suffered physically. A medication like this one would help me and others like me, it has nothing to do with trying to look like a supermodel, just maybe it could make some peoples' lives somewhat "normal".

Getting buff without the sweat is cheating

Scott, Cincinnati 4eva, OH — Thu, 07 Aug 2008 16:36:48 GMT

we all can't live forever. The "we could save millions of lives" ideaology leads to overpopulation quickly (jar of flies experiment) so suck it up and eat right and exercise somehow someway, as much as you can. maybe you live longer, maybe not. Either way you ain' gonna live forever, so suck it up and bite the natural bullet.

Getting buff without the sweat is cheating

Effort, Los Angeles — Thu, 07 Aug 2008 16:37:12 GMT

Pills,pills and more pills! Come on how about trying to accomplish something yourself! I fully agree that there is some use for such drugs, i.e. injured/ill person whos' mobility is limited. But people, get off your lazy gluteus maximus and get moving!We're all busy and it is too easy to blame things, looking for an easy way out. “Seeking itself is the goal.” What a good statement!

Getting buff without the sweat is cheating

Mary, KCMO — Thu, 07 Aug 2008 16:43:52 GMT

If this turns out to work the same with humans, I say great!

I don't think that people who because of illness or physical limitations (arthritis, injury) would use this to keep from exercising. I think they would be thrilled if it helped them to get around a little better and in the end, would result in them becoming more active, too.

I have advanced arthritis in my back with bone spurs on my spine. My lower back is fused, but with permanently bulging discs. The only exercise I can do without pain is to swim at the gym. If this pill made it so that I could burn more calories and have a better workout, it would be fantastic!

But I also think of those with MS or other conditions where the muscle is deteriorating, these people could use the help.

Make it available when the tests are through, but control it by doctors to those who really need it, not for those who are trying to beef up their workout.

Getting buff without the sweat is cheating

Joel, Harrisburg, PA — Thu, 07 Aug 2008 16:47:37 GMT

Getting buff without the sweat is cheating

GDoe — Thu, 07 Aug 2008 16:48:04 GMT

Like Paul my joints ache all the time, with or without a workout. I've decided to ache and be in the best shape I can for as long as I can until I can't.

Getting buff without the sweat is cheating

Erica, Denver, CO — Thu, 07 Aug 2008 16:48:35 GMT

Really? Isn't this how they originally advertised cocaine?

Getting buff without the sweat is cheating

Trapalon — Thu, 07 Aug 2008 17:06:22 GMT

So it creates muscle fiber and promotes cellular growth? It makes me nervous to have cells in my body reproducing unnaturally. I'm no expert but I smell cancer.

Getting buff without the sweat is cheating

Kary, Raleigh, NC — Thu, 07 Aug 2008 17:11:48 GMT

One of the impacts of these studies was a reduction in body fat, for at least one of the 2 drugs. Since our culture is making us fat as a nation, I think we will need this sort of drug as yet another tool in the toolbox as we try to fight obesity

Getting buff without the sweat is cheating

Nathan, St Paul MN — Thu, 07 Aug 2008 17:12:39 GMT

I am 240 lbs and 6 ft tall, aprox 40 lbs over weight, I have been working out since April fairly regularly, and I have achieved some results (I'm a toner 240 then I was when I started.)

I would buy this pill in a heart beat, not because I want to stop working out, but because I want more resutls when I DO work out ...

Getting buff without the sweat is cheating

John Doe, Seattle Wash — Thu, 07 Aug 2008 17:13:46 GMT

So hey, if you have a thing for racing mice on a treadmill, this article may be significant

Getting buff without the sweat is cheating

J, LR, AR — Thu, 07 Aug 2008 17:31:11 GMT

Let's just add it in all foods like they do vitamins so we will have a country of huge people. Maybe then all the other countries would be afraid of us.

Erica from Denver gets the quote of the day.

Getting buff without the sweat is cheating

Russ — Thu, 07 Aug 2008 17:36:40 GMT

Resveratrol, found in dietary supplements, red wine, and other fruits and vegetables, has been proven to extend life span and reduce the risk of cancer, heart disease, alzheimer's disease, and diabetes (i.e. the diseases of aging). I take a resveratrol pill every day as I stongly believe that it is the future of medicine.

Getting buff without the sweat is cheating

Larry Lewallen — Thu, 07 Aug 2008 17:47:51 GMT

What a great idea. Sign me up. Lets face it - I'm over weight, and, if I was going to start going to the gym and exercising 5+ hours a week while watching what I eat I'd already be doing that.

If made available, this drug would likely begin lowering the healthcare costs for millions.

Getting buff without the sweat is cheating

Scott, Philadelphia, PA — Thu, 07 Aug 2008 17:59:14 GMT

Maybe it's just me, but if everyone is buff and looks like a supermodel, then where is the advantage in looking buff or like a supermodel? If you're looking to drugs like this simply for looks, then it's pointless, because if it's widely available, then those 5% looks won't be 5% anymore. If you want it to be healthier, then more power to anyone who chooses to use it. You have to be happy with yourself, and those that use it as a cheat, will have to know in their own minds that they cheated. Those that truely want it for a more "noble" purpose won't have the guilt associated.

Getting buff without the sweat is cheating

TM, Chicago, IL — Thu, 07 Aug 2008 18:18:03 GMT

I don't find this to be a huge surprise with all of the advancements in technology and medicine. I'm sure there will be more wacky ideas and pills to come along. I really feel like this drug will be slightly expensive and probably covered by insurance if you need something like this. It doesn't worry me a whole lot that something like this is out there right now. My bet is that most people won't be able to afford it - again unless it's covered by insurance for a medical need. I don't think I'd bother to go out and get a bottle of the stuff unless I could go pick it up at GNC or some convenient place like that. If I had a condition that made it so that I would really need this then of course I'd be interested. As it is now, I'm not interested and I feel like a lot of people won't bother unless it's readily available and reasonably priced - which I can't imagine that this would come without prescription and a high cost.

Getting buff without the sweat is cheating

Steve Bethel CT — Thu, 07 Aug 2008 18:21:11 GMT

Guinnea pig, I am all for it!

Pass the pill and let me go to the Gymm..

Getting buff without the sweat is cheating

Kent, NP, IN — Thu, 07 Aug 2008 18:34:30 GMT

The answer for semi-healthy people is not a pill. Go do some real work. Go for a walk, do some pushups or situps. This country is full of lazy people. I'm glad to not be one of them.

Getting buff without the sweat is cheating

Allen McCready, Pittsburgh, PA — Thu, 07 Aug 2008 18:55:01 GMT

Hey...if God wanted man to fly, God would have given man wings. Wait...he did. He gave man a brain and an opposing thumb with which to build wings. Similarly, if God wanted man to wear clothes, he would have given him clothes. Wait...he did. He gave man a brain and an opposing thumb with which to make clothes. Etc.

For those who enjoy working out just to work out, there is nothing to prevent them from still doing so even with such a pill available, just as there is nothing to prevent people who earn big bucks from also enjoying just looking at their big bucks as well.

I think those who will feel most cheated by such inventions are those born with the results already in place, or the time to make the improvements, or the money, etc. Their edge over others in this case (a muscle pill) will be but momentary and such edges are not yielded easily.

(Many of my past comments have never been published. It will be interesting to see if this one makes it. This is my 2nd try today to get my comments on this to appear. Perhaps there is a pill for this condition too...no not for me, for the comments reviewer.)

Getting buff without the sweat is cheating

Clifford Williams, Collegedale, Tenn — Thu, 07 Aug 2008 18:56:16 GMT

My concern is that people using these pills to make their muscles more fit will end up less fit in mind-body awareness. It won't do you any good to make your muscles more fit while you lose your coordination.

Getting buff without the sweat is cheating

CHRISTINE FRAME BELLEVILLE ,IL — Thu, 07 Aug 2008 18:56:33 GMT

IF IT IS NOT GOING TO BE HARMFUL AND THE PRICE IS RIGHT. I WOULD TAKE IT.

Getting buff without the sweat is cheating

J,, Bethesda MD — Thu, 07 Aug 2008 18:59:14 GMT

There is a big difference between muscle mass and muscle tone. It sounds like the drugs help increase muscle mass and increases endurance, but you're not going to get 6-pack abs. It's like they tell people who do sit-ups to try to spot reduce: muscle covered with flab is still flab. On the other hand, this could encourage people to exercise more if they have more endurance and see more weight loss due to the increased muscle mass.

Getting buff without the sweat is cheating

Mike, Elkhart, Indiana — Thu, 07 Aug 2008 19:00:58 GMT

Imagine the implications for future space travellers. You could take a pill that would diminish or negate the effects of weightlessness on the body. Combine with a high-uptake calcium suppliment, you could remove the symptoms of long-term weightlessness altogether.

Getting buff without the sweat is cheating

Brent, Memphis TN — Thu, 07 Aug 2008 19:04:02 GMT

What separates man from beast? OUR MINDS!

That being said the concept of "cheating" when applied to this is laughable. If i, using my mind, can gain the benefits of work without doing work and without it harming a 3rd party i have not "Cheated" i have EARNED it though superior intellect and design.

Getting buff without the sweat is cheating

Will, Texas — Thu, 07 Aug 2008 19:11:13 GMT

Don't ever complain about having to put time into exercise. An hour a day is more than enough to be in good shape. crossfit.com has many excersies that take less than 20 minutes. yes you need a gym for many of the streangth exercises, but you can always buy your own weights, and substitute other excersies in for the wieghts you dont have.

Nutrition is 65% of the battle, and if you really put the numbers together eating healthy is cheaper than eating the garbage that most of you probably eat. When you subtract chips and candy from your bill, you add a lot more money for the healthy alternatives.

Joint problems are often fixed with excerise...it's proven.

If you don't enjoy exercise it's because you were either doing something very boring AKA military PT or you were in the process of losing weight in which your body is so used to sitting down that it takes time to get to the enjoying part.

And for the people that have legit problems that arent casued by obesity and overeating. I truly am sorry, but thank your parents for your bad genes.

Getting buff without the sweat is cheating

Melynda, Edmonton, Alberta — Thu, 07 Aug 2008 19:14:18 GMT

In my younger years, I played soccer 7 days a week for over 20 years. Sometimes playing two games a night. After having to fight leukemia at an early age, I found that I had to work twice as hard as everyone one else just to be normal. With that being said, my work ethic is fantasic.

Fast forward to last year, I tore my ACL in my knee playing soccer. I have to get surgery. However, because of the chemo and other underlying causes, I have developed a rare blood disease and surgery is not an option.

So I am left with not being able to play soccer. Going for long walks or runs are painful and I have gained 30 lbs in the last year from not being able to do any of the phyiscal activity I enjoy. Toss in family and working two jobs and I dont really have the time to go to the gym.

However, having to take a pill for the benefits of exercise, I am all for, but dont get me wrong, it is not going to replace the happiness and the strength I feel when I walk on to the pitch.

Getting buff without the sweat is cheating

Jim, Washington, DC — Thu, 07 Aug 2008 19:15:33 GMT

In a few years (or once human trials start) they'll find out about some side effect that negates all of the benefits. Maybe this drug will make your head explode.

If it sounds too good to be true, it probably is.

Getting buff without the sweat is cheating

AHHNOLD SCWHARZENEGGAR — Thu, 07 Aug 2008 19:20:25 GMT

What a hypocritical society we have become. We Americans bash with angst the athletes and bodybuilders who want to have an edge and look better and perform better in the gym or on the field by using steroids. But promise the McDonald eating masses exercise in a pill and they foam at the mouth. What is the difference with this and PEDS, or steroids for the nonenlightened. Steroids have been around since the 1940's and have years of studies to prove them as being relatively safe. But because ole Barry hit a few to many homeruns, they are considered worse than heroin. Offer the mindless sheeple exercise in a pill and they are all ready for it. What a freaking joke.

Getting buff without the sweat is cheating

tony — Thu, 07 Aug 2008 19:24:30 GMT

Oh boohoo, if you want to exercise that's your privilege for the rest of us it's our business if we don't. Quit moralizing over what's right for everybody else,or are you the people living with your girl friend or what?

moralizing

Getting buff without the sweat is cheating

Fit Bottomed Girls — Thu, 07 Aug 2008 19:25:47 GMT

The idea is enticing on a base level, but I don't think I'd ever stop working out.

Getting buff without the sweat is cheating

Scott, PEI, Canada — Thu, 07 Aug 2008 19:32:02 GMT

I'm all for it. Give them out by the bucketfull for free if you have to. Anything that will make people healthier instead of sicker gets a thumbs up for me. The economy will also get a generous boost by eliminating alot of obesity and type 2 diabetes and a myriad of other weight issues from the health care systems. Personally, the only people who wont like this are the hot looking buff types cause all of a sudden they aren't so unique anymore. There'll be a lot more hot looking folks running around, and that cant be a bad thing for anybody, other than the jealous ones.

Getting buff without the sweat is cheating

glutton01 — Thu, 07 Aug 2008 19:32:23 GMT

this would be a big boost to the economy... think of how much more beer and food I could consume without losing my girlish figure. A scientific spin on the Roman vomitorioms of old. Goodbye Anorexia. Sweet.

Getting buff without the sweat is cheating

Nick Marks, Youngstown OH — Thu, 07 Aug 2008 19:33:41 GMT

I can already see the problem here:
"If I take 1, 2 will be better."
"If I take 2, 4 will be better."

You figure out the rest.

Getting buff without the sweat is cheating

Jack Schneebeli Caldwell, Texas — Thu, 07 Aug 2008 19:43:23 GMT

We are currently involved in the biggest doping scandals in sports. We are going to attack this problem with drug testing while developing other drugs whose results are easier to obtain (no effort required) ??????? With thes drugs a person of descent athletic ability would be able to go through a regular workout to stimulate the bodily reaction: pop, inject, inhale the prescription. When the body recovered you would be operating at a level that was above your nondrug induced paramenters. I am sure athletes of all abilities are dying to run a few cycles of these drugs.

Getting buff without the sweat is cheating

Colleen, West Islip, New York — Thu, 07 Aug 2008 19:45:08 GMT

I just get a little upset that we don't have a cure for diseases that are really aweful, like alzheimers or cancer, and yet research dollars and scientific brain power are being (IMHO) wasted on trying to make us look sexy? Get to the gym and put down the donut, people. Let's get our scientists engaged in research that improves the human condition, not that coddles the human ego.

Getting buff without the sweat is cheating

Kirk, Phoenix, AZ — Thu, 07 Aug 2008 19:51:48 GMT

Taking a pill is cheating? I guess the same could be said about driving a car, using a dishwasher, or turning on your air conditioner.

This is just another technical advance, that I would love to get my hands on.

Getting buff without the sweat is cheating

ART San Diego — Thu, 07 Aug 2008 19:53:08 GMT

Blah, blah, blah...where can I get some? I'll pay anything. I'll get my law degree instead of going to the gym thank you very much. That way, I can be hot AND wealthy. Wooo-hooo!

Getting buff without the sweat is cheating

KateR, Ann Arbor, MI. — Thu, 07 Aug 2008 19:53:55 GMT

I would take this drug for a limited amount of time - it's the grueling long haul to gain endurance for exercise that makes so many people quit at the gym. If I could start off at a higher aerobic capacity I'd be 100 times more inclined to continue an exercise regimin.

Getting buff without the sweat is cheating

Tappy McWidestance — Thu, 07 Aug 2008 19:54:51 GMT

If you have a serious condition that actually prohibits you from exercise, sure whatever... I guess that's okay if it's going to enhance your health. But to all the lazy people that make excuses ("no time", "wah, I don't like to exercise", whatever), to pop a pill to get into shape is simply pathetic. I don't like to exercise, but I'm not about to sink to the level of sitting on my lazy rear and pop a pill in hopes of a six pack. Have some dignity for yourselves people, no wonder the rest of the world thinks we're fat and LAZY!
Joel, Harrisburg, PA (Thursday, August 07, 2008 12:47 PM)

______________

Hey Joel - BITE ME! Dignity isn't based on a six pack or the opinion of a musclehead who has nothing better to do than workout. If the pill helps keep people in shape and out of the doctor's office then that is all that really matters.

Getting buff without the sweat is cheating

Angela, Littleton, Colorado — Thu, 07 Aug 2008 20:44:40 GMT

I have had my spine fused one knee surgery and I have to have the other knee operated on. This within a two year span. I myself like others was very active when I was younger. I have to have spine injections and I am also on narcotic medication everyday for pain. So having a pill to help without having to indure pain. YES MOST DEFINATLY!!!!!!!!!!!!!!!!!!!!!!!!

Getting buff without the sweat is cheating

Big Dave, Tampa, Florida — Thu, 07 Aug 2008 20:52:22 GMT

I have a feeling that the small print will say something about anal seepage or something equally disgusting. You know it can't be all good!

Getting buff without the sweat is cheating

J T Gillespie — Thu, 07 Aug 2008 20:58:38 GMT

I am 53 years old and have been taking Transmax resveratrol from Biotivia for about one year now.
I now cycle every day and feel like how I did when I was a teenager. I feel like I have enough stamina to go all day without having to rest.
I seem to be on a natural high all day long without being tired and sleep so well during the night.
My old aches and pains have vanished (especially in my knees) and I generally feel like I have been given a new start in life.
Doctors and researchers all over the world are testing this natural product out on themselves so why should we wait until they tell us about the benefits?
Have a search on the internet for Resveratrol and you will be amazed.

Getting buff without the sweat is cheating

Neal, Boston, MA — Thu, 07 Aug 2008 21:20:29 GMT

hmm. So barbells should be refused because lifting rocks is more natural? And running on a track is less valid than, oh, say, getting chased by an angry cavewomen's father. Please. The objective is being fit and healthy, not smelly.

Getting buff without the sweat is cheating

Cully Miller, Tampa, FL — Thu, 07 Aug 2008 21:41:03 GMT

I'm sure the mice were thrilled to be subjected to "test" drugs, held captive, and forced to run on a treadmill so some pharmaceutical company could make billions of dollars. This is sooo wrong... on sooo many levels. Animals do not exist for human purposes -- they exist for their own. Stop torturing animals. Support cruelty-free products.

Getting buff without the sweat is cheating

Paul Lero, Kansas City, KS — Thu, 07 Aug 2008 21:46:29 GMT

So is the carrot before the horse or vice versa? People with more muscle and stamina tend to workout and exercise more because it is less stress on their systems, anything that helps someone to become more fit and active is worth checking into as long as there are no long term health problems associated with it so where is the cheating, one hand in this case washes the other and would benefit an aging less active population!

Getting buff without the sweat is cheating

Sara M. Baltimore, MD — Thu, 07 Aug 2008 21:46:45 GMT

Speaking from experience - I have steel plates in my femur and bad discs from L-4 to L 6 making my past excercize efforts impossible and the pounds creep on. It would be great for me to have some help like this. I don't see many "Gym rats" willing to date a great gal with a few extra pounds

Getting buff without the sweat is cheating

Paul Lero, Kansas City, KS — Thu, 07 Aug 2008 21:47:15 GMT

Getting buff without the sweat is cheating

Ashley, Colorado — Thu, 07 Aug 2008 22:10:41 GMT

Hmm, the idea is really enticing. I love to run, ride my horses and do light weight reps, but this would make a great supplement to all that. I do wonder though, if it'll just end up contributing to the cycle of unhealthy living in this country. You know, eat fast food every day, never get off the couch -- but you can still take a pill and you can never learn the consequences of your life choices. Seems to me we're all missing the bigger concern here.

Getting buff without the sweat is cheating

ChiefTom — Thu, 07 Aug 2008 22:42:05 GMT

I have been fat all my life and I would give just about anything to just be normal. No six pack, not buff, just normal.

It is so easy for people that have not had to live this life to point fingers and call us lazy or weak. Maybe they are right, but there are a lot of skinny people that are lazy and weak but it is not a death sentence for them.

Think of the millions of lives that would be extended, think of the billions of dollars that would not be spent on health care.

How could anyone in their right mind value professional sports over the lives of real people?

Getting buff without the sweat is cheating

Sharon, Lynnwood, wA — Thu, 07 Aug 2008 22:52:13 GMT

The old saying "If it's too good to be true; it probably is." As much as I would like a drug to help me look "buff" I'm concerned with the possible side-effects. I've had a weight problem all my life and I've had to run and lift weights all my life. I still don't have the abs of stell or have a flat stomach. I'm getting older and I have more aches and pains then I'd like. If this pill could help push me over the edge to look better I'd take it. As someone mentioned above I would like to wait a few years to make sure it doesn't damage my heart of other vital organ. As with anything dealing with weight loss it will still require the person to eat moderately and exercise.

Getting buff without the sweat is cheating

Jake, VA — Thu, 07 Aug 2008 22:53:01 GMT

ok fine for you. Those exacting standards applied in job interviews, loan interviews, dates; to look not only fit but young, well I guess you'll be one of those losers with no job or friends then. The standards for human interaction will not change, no matter how much disappearing up your own behind you do with philosophy. Some of us prefer having advantages, AND working hard to be winners. If you don't- that's your choice.

Getting buff without the sweat is cheating

Debbie Cooperstown, pa — Thu, 07 Aug 2008 23:00:46 GMT

let me experiment with it to see if it is all you are saying it is.

Getting buff without the sweat is cheating

P, CA — Thu, 07 Aug 2008 23:13:15 GMT

This may sound trippy, but people don't seem to understand that food is really a drug in and of itself. You consume foods to "dose" your bodies with recommended allowances of vitamins, proteins, carbohydrates, water, and other things. Creating drugs to supply your body with aid for bad genetics or bad habits (that may be hard to get rid of with your daily schedules/routines) isn't really all that bad, but the biggest problem is addiction. If these pills were addictive or caused people to be irrational, there may be a big problem there. I'll be first in line to try it, but if there's an issue, I'd hope that the companies peddling it would also have the scruples to pedal a cure if they cause a mess. Anyway, just my two cents.

Getting buff without the sweat is cheating

Kevin, Navarre, FL — Thu, 07 Aug 2008 23:47:04 GMT

Ok, time to set aside anachronistic convictions about pills for a while and look at the benefits of the drugs that we've developed. How can it be considered a bad thing that a pill's been developed that can increase overall health, without sacrificing worker productivity and crunching everyone's time? Because of these "lazy" pills, older men no longer deal with impotence, people are able to lift themselves from clinical depression, we're able to utilize birth control, we can fight Alzheimer's syndrome, and we can lower people's cholesterol. I suppose there will always be people who feel that progress is a bad thing.

Getting buff without the sweat is cheating

Susan L Cronin, Frostproof, FL — Thu, 07 Aug 2008 23:55:19 GMT

If this pill can help people who are ill and unable to exercise then I am all for it. My best friend has Lupus and has lost all her muscles from lack of exercise. I pray that they put this pill on the market soon and that it is proven to help people like my best friend.

Getting buff without the sweat is cheating

Kaelinda, Romney, WV — Fri, 08 Aug 2008 00:00:27 GMT

I have a lung disease called "BOOP" (bronchiolitis Obliterans with Organizing Pneumonia) that causes me to run out of breath at the slightest exertion. In addition, my back was broken in 2005, and while the vertebra has healed, it still hurts to stand up for very long. And I have a pinched nerve in my back, which makes it hard to walk because my legs hurt. As a result of not being ABLE to exercise, I've gained 50 pounds - I'd take a pill to help get rid of the extra weight and to let me feel like I have exercised. Being on steroids doesn't help, and when and if I ever get off them, I'll probably lose some of the weight "automatically."

Getting buff without the sweat is cheating

Fred - Chicago, IL — Fri, 08 Aug 2008 00:12:52 GMT

So is it cheating to use Penicillin instead of letting an infection run its course?

Getting buff without the sweat is cheating

terrance mills, sioux city, SD — Fri, 08 Aug 2008 02:19:11 GMT

Who are you to judge Bill Goldberg. Bla Bla Bla.

Getting buff without the sweat is cheating

Jon, Denver, CO — Fri, 08 Aug 2008 02:49:44 GMT

How is this bad? If the side and long term effects aren't too problematic, why not use it? The only people that would have a problem with this are elitests. The benifits that could come from this would be incredible, less health care spending, less mental anguish for those that can't exercise for whatever reason, and those are just the tip of the iceburg. Think of how much health-care spending would plummet for everyone!

As for not recieving the "other" benefits of exercising as stated above, so what? Would you rather be depressed and normal sized, or obese and terrified of walking out your door due to the discrimination these people suffer AND depresssed on top of that? It's not a hard question.

If I could find a human trial, I'd enroll in a picosecond. Even if it does shorten lifespan a bit, what good is a longer life if the quality of that life is horrible?

Getting buff without the sweat is cheating

FibroFog, Chicago — Fri, 08 Aug 2008 03:58:17 GMT

I have fybromyalgia and have gained weight becasue exercising causes excruciating pain. I have no medical insurance, so I cant get the physical therapy I need to get the pain under control. This would give me an option to start a positive change.

Getting buff without the sweat is cheating

Samantha, San Diego, CA — Fri, 08 Aug 2008 04:00:52 GMT

Just having more endurance would make playing sports, engaging in physical activity and, yes, even working out, so much more rewarding for those of us who were not blessed with strong bodies and are sick. Also, as Kary mentioned, the reduction in body fat would improve the quality of life for so many and reduce the instance of many diseases and health problems!

Getting buff without the sweat is cheating

Douglas Schmidt — Fri, 08 Aug 2008 07:47:46 GMT

Since the Dr. Sinclair study was published in Nature a flood of dubious companies have sprung up selling resveratrol. Many have no scientist, no labs, no quality control and no experience. Consumer Lab, an independent testing authority, evaluated the major brands and found many lacking in content and quality. The highest potency products that passed their evaluation were Biotivia, Transmax and Bioforte. A product by Life Extension Co. failed badly with only 26% of the claimed resveratrol. Another brand, Revatrol, had virtually no trans-resveratrol in its supplement. The ConsumerLab test results are available on their web site.

According to the NIH formula for converting from mice to humans the correct dose based upon the published studies is between 400mg and 4,000mg for a 70 kg man. The consensus seems to be that around 1,000mg is appropriate for a preventative dose and twice that to treat an existing condition.

Getting buff without the sweat is cheating

Ellen, OK — Fri, 08 Aug 2008 07:51:23 GMT

I enjoyed a *very* active lifestyle and a healthy body well into my 20s when a drunk driver took that from me. I would almost do anything to lose the 125 pounds of blubber, lost mobility, and deteriorating health I've been left with since. I eat practically nothing already and exercise is a joke trying to lug this gross body around equipment made for people half my size with people rudely staring at me. If this pill can get me down to where I can start working out again safely and comfortably and then help me get back into shape while I burn the rest off, then I'm all for it. I'd rather die testing a fat-burning, muscle-building pill that might give me a chance at a healthier, happier life in the end than die 10 years from now from a stroke as a quarter-ton fat lady stuck in bed.

Getting buff without the sweat is cheating

Douglas Schmidt — Fri, 08 Aug 2008 08:47:20 GMT

Getting buff without the sweat is cheating

Dustin, Indianapolis, IN — Fri, 08 Aug 2008 09:24:37 GMT

This might help astronauts maintain muscle mass during long term spaceflights.

Getting buff without the sweat is cheating

Joshua Frazer, Washington — Fri, 08 Aug 2008 09:58:06 GMT

Is using the telephone to talk long distances cheating? Is using a car to move faster cheating?Is using a computer to do your finances faster and more accurately cheating? Is using a book or the internet to quickly find information instead redevloping all human achievment yourself cheating? Why is something that can amplify your results & productivity cheating? If it can improve people's quality of life, help them achieve their goals, and aid in living longer and healthier, then I say it's a good thing. Stop making exercise into a sacred cow, you fanatic purists. Act like a doctor or professional and use reason.

Getting buff without the sweat is cheating

Robert, Dallas, Tx — Fri, 08 Aug 2008 11:18:04 GMT

Our culture isn't making us fat. WE ARE! If the drug were capable of helping people who have prohibitive conditions or serious medical problems good, but if you think back how many miracle drugs have been recalled in the last five years when people start dying or having serious side effects. And Kary if you want to start changing our culture, get off your butt and start setting an example for your kids. By the way I have a bulged disc impinging on a sciatic nerve, I control it and have improved the condition through regular weight training.

Getting buff without the sweat is cheating

NJ — Fri, 08 Aug 2008 14:09:07 GMT

Just like Viagra, they say they are developing it for specific medical conditions. Just like Viagra, they'll sell it to anyone with the money to pay for it. The dollar is the bottom line, and somehow it is doubtful that insurance companies will pay for a perceived recreational medication even for those who truly need it due to muscle disease etc.

Getting buff without the sweat is cheating

Fri, 08 Aug 2008 14:26:39 GMT

I completely agree with Kary, America as a nation is becoming increasingly more obese and more sedentary. We try to promote exercise and tout its benefits but largely our culture seems to be diverging from that path to hit the drive-thru McWindow.
Advocating this drug as an over the counter option to laziness would likely reduce the obesity problem in the short run, but in the long run would likely cause many more problems by interrupting the need to look after oneself and personal health. That kind of large scale movement away from personal culpability of ones own actions (again not referring to those would take it out of medical need)could very well weaken us as a people by redefining the socio-economic roles, and boundaries, and not necessarily for the better.

Not to be all doom and gloom but im sure we can all recall various adages regarding thing gained without merit. Interestingly enough id like to hear the military's opinion on a drug that has the potential to bring them one step closer to creating 'super' soldiers.

Getting buff without the sweat is cheating

Sara, Phila, PA. — Fri, 08 Aug 2008 15:01:24 GMT

I fear that developing a pill like this one for the general public would prove harmful in the long run. It may be a quick and easy path to a thinner body, but the benefits of exercise go way beyond just looking good physically. Heart disease is the #1 killer of American women and is estimated to claim the life of 1 in 3 women. Exercise improves circulation and strenghens not only the heart, but all the muscles of the body. It's a no-brainer. You MUST exercise the heart muscle in order to keep it healthy! Yes, a pill would certainly be a quick fix to a leaner, more attractive body. I fear though, that a pill like this would cause many women to stop exercising altogether and put them at great risk for cardiac disease. When it comes to my health, I'm just not willing to compromise.

Getting buff without the sweat is cheating

Jerrold, Cleveland, Ohio — Fri, 08 Aug 2008 15:50:48 GMT

I'd love this drug in combination with my exericse program, though. I don't have endless hours to spend at the gym and my aging (40) body is starting to show the signs. It'd be great to supplement my 3-4x a week gym regiment with this to keep me in better shape and help shave off some pounds.

Where do I sign up!? :D

Getting buff without the sweat is cheating

Injured, AZ — Fri, 08 Aug 2008 16:33:39 GMT

I'm a firefighter who got injured on the job and have been laid up injured for 6 weeks. The doctors and physical therapists think it will take another 6 weeks or so to heal. During this time I have not been allowed to workout or execise at all. It's going to take me several months to lose the weight I put on as well as to get back into shape. Had a drug like this been available to me to use while healing I would have used it. My being in shape is a necessity as peoples lives are affected by what I do. I don't condone the idea of purely using the drugs but, as a support system for those injured or with debilitating diseases I can see a legitimate use for them.

Getting buff without the sweat is cheating

Dani, St. Louis MO — Fri, 08 Aug 2008 17:15:17 GMT

My sweet old dad is in his mid-late 50s, has an adopted 8-year-old son, has a very demanding full-time job (director of 3 departments at a hospital), is an Alderman of his town, is heavily involved in the church, is a member of several civic groups, helps take care of his elderly mother-in-law who lives with them, and is solely responsible for all of the yard work and home improvement projects of the new house they just bought. The poor guy is running himself ragged. He has high blood pressure, high cholesterol and has already had a stent placed in two of his coronary arteries. He's a heart attack waiting to happen. He knows he should exercise, but rarely has time to take care of himself at all. If this drug were available, I'd be the first in line to get it for my dad. I don't care if it's "cheating." He's the only dad I've got; I love him and want him to be around at least another 20 years or so. If this drug could make it happen, you can bet your sweet patootie I'd be getting it for him.

Getting buff without the sweat is cheating

Andy B, St Paul, MN — Fri, 08 Aug 2008 20:17:07 GMT

Does it work on all the muscles? how about ones used for breathing? Many people are unable to or cannot tolerate even moderate excercise. Two examples:
1 sould it help premature babies develop more lung strength?

2) How about people with COPD who breathing muscles wear out from the exertion of simply breathing, and are using BiPAP (a step just below a ventilator) to give their muscles a chance to rest and recover from the overwhelming effort to just breathe. Forget about walking or climbing stairs! What would you give for another week of survival if such a drug helped even a little bit??
Or a third use maybe in spinal cord victims it can help maintain muscle mass in the affected limbs? Remember Christopher Reeve's using electric stimulation to maintain his leg muicles and prevent deteriation so that he could benefit form new therapies when available to regrow his nerves, even if such miracles are far off, I imagine many other tyupes of patients could benefit from increased muscle endurance but not be able to do the excercises to gain such muscle due to their health or diasbilities . Such a drug may improve not just their endurance but their quality of life.

PS: another use I jus thought of:
what about space exploration? sure we may find a way to get humans to "hibernate" or suspend animation, but what good is it if you wake up helpless as a baby from muscle degeneration?

Remeber astronauts are very weak after returning from extended time in Zero Gravity and not just because of chnges to their bone density...

possibilites in the basic research into such drugs as this instead of hyping the negative possible uses of a drug

what about spinal cord injury victims to maintain their muscle mass until a cure or device can restore lost spinal function? Stem cells hold promise I am sure or maybe human machine solution but Remember Christopher reeves? how he had his legs stimulated with current to keep them strong enough to be useful for when a cure was devloped?

Well this is the type of science reporting that makes me want to vomit. I suppose you are one of the people who ridiculed Provigil, a drug that promotes wakefullness as a utopian pill for college students trying to cram for exams or for truckers who don't like the jitters from amphetamines. Instead of a useful drug for people suffering from narcolepsy. Whats next ativan a drug that produces pschoactive reaction of wellbeing but also is good for treating acute seizures?
What about this article celebrates the science involved and help it gives people trying to understand the basic physiology of the human body, or biology in general as so much is dependent on muscles from breathing to walking it sounds like a incredible breakthrough.

Getting buff without the sweat is cheating

canada3dayer, Bonaire GA — Fri, 08 Aug 2008 20:20:39 GMT

I for one would love something like this. and before you get the idea that I'm lazy, I'm not - my weight gain is solely due to my work schedule, which requires me to be at work at 6am, so I have to get up at 4:30 am. I have a horse and I have a dog, so I get plenty of exercise. it's the lack of sleep that's put on the pounds for me. and given the added of running a household, albeit one that includes only me and the animals (horse, dog, 2 cats), all that still takes time, so I don't have the time to spare to go to the gym.

Getting buff without the sweat is cheating

Ali Morgantown, WV — Fri, 08 Aug 2008 20:42:00 GMT

I am in the Army. I have one question, who in the hell likes exercising? Frankly, pain in the joints and being short winded for long periods of time are not my idea of fun. I do notice I get moody however if I do not exercise. I think my body is addicted to pain. I would take the pills in a heartbeat if they were cheap enough. But I agree with the one reader, I smell cancer too. But hell I lived next to a power plant for over a decade. I am probably going to get cancer anyways.

Getting buff without the sweat is cheating

Geni Panama City, FL — Sat, 09 Aug 2008 01:13:40 GMT

Imagine what this could do for all of those extremely obese people you see on TV who cannot even leave their bed and haven't walked in years, much less excercise, what if this could give them the ability to get their muscles working and get that weight off that is killing them, what if it could give them another chance at life. I think it could be a wonderful thing for so many, I'd give it a try for sure, I belong to a gym but with my hectic work schedule and taking care of a family I'm just paying for a membership I can't use, I'd like to but can't find time. Also the heart is a muscle, what about people who's hearts are weak and giving out, what if it could help them, wouldn't you want to see that happen, I think everyone knows someone with heart disease.

Getting buff without the sweat is cheating

Michael, Los Angeles — Sat, 09 Aug 2008 02:27:35 GMT

this article could be condensed into about 3 sentences.

Getting buff without the sweat is cheating

Dex Marston Austin, Texas — Sat, 09 Aug 2008 19:34:19 GMT

Why do many of you react as though you're part of a herd of cows? Get over your fears of armagaeddon and let science develop and evolve without your constant whining! If you don't want to take the pills, don't and the rest of us can make our own decision about this and EVERYTHING ELSE!

Getting buff without the sweat is cheating

docyap — Sun, 10 Aug 2008 19:26:03 GMT

i'm in a medical profession and i agree with paul (post 7/8/08). i've got a couple of years before i see 50 but due to weird and, so far, uncontrollable allergies that keeps me itching 24/7 and has left me scarred from open, oozing skin wounds - i was on steroids for about 3 years and my weight has ballooned to 220 pounds (normal for me is 90-100 pounds less than that). i've since developed diabetes, high blood pressure and now have arthritic knees. the inability to exercise like i used to (run, bike, swim and paddle-the sun, heat and sweat exacerbate my allergies) coupled with the medical issues has also fueled a spiraling depression. having a pill that will help drop the pounds so that not only will i feel better but i will be better is a miracle. can't wait 'til it's on the shelf.

Getting buff without the sweat is cheating

Wrestler, Los Angeles, CA — Sun, 10 Aug 2008 20:21:16 GMT

Don't get your hopes up. The ill-informed jugheads in congress will schedule this drug like they irrationally did with steroids. It should be available to all who wish to use it under the supervision of a doctor for improving their physical condition and appearance. But - as happened with steroids - mythology, misinformation and political agendas will take this drug out of the hands of all but those who are on their death bed.

Getting buff without the sweat is cheating

Michael Iacono, Collingswood, NJ. — Sun, 10 Aug 2008 20:36:25 GMT

I'm 71 and cannot exercise as I should. Who makes these drugs and when if ever will they be available. Like many, my age, I am limited because of pain, that exercise would help. I'm between a rock and a hard place - like many.

Getting buff without the sweat is cheating

Bunny, Winston-Salem, NC — Sun, 10 Aug 2008 20:46:01 GMT

To Deborah Shupe: I have been through the same routine you have for the past (2) years. I'm 53. I don't want to look like a super model. I would just LOVE to be able to do some of the things that I once did...like walk without excruciating pain and go back to work. Being on disability stinks.

Getting buff without the sweat is cheating

Jeanne, Media, PA — Sun, 10 Aug 2008 21:51:55 GMT

At one time many things were considered cheating rather than progress by a puritanical segment of the population intent: buttons, automobiles,sewing machines, typewriters, calculators, e-mail, audio books, e-books - the list is endless. If you don't agree with it then don't use it, but stop forcing your views on the rest of us.

Getting buff without the sweat is cheating

Art Wheeler, Dayton, OH — Sun, 10 Aug 2008 22:44:04 GMT

When health truly necessitates it, okay. But merely for the purpose of getting buff without the effort? Or to glorify and reward laziness? Or in a vain attempt to avoid the eternal struggle to maintain balance in our lives? Pointless. As with so many aspects of life -- and indeed life itself -- the journey is far more important than the destination. After all, we all end up dead. It's how we get there that makes all the difference. As trite as that may sound these days, it's no less true. "Being" buff is not the goal that matters. "Getting" buff (or staying buff) -- i.e., the journey -- is what provides meaning. And a "journey" of pill-popping falls woefully short of qualifying as meaningful.

Getting buff without the sweat is cheating

Steve, Detroit Mi. — Mon, 11 Aug 2008 01:06:21 GMT

love all the other posts giving reasons why they would take this....but honestly, I'm just fat and lazy and a wonder drug that gets me in shape while on the couch is a godsend in my books! BRING IT ON!

Getting buff without the sweat is cheating

Nick Green — Mon, 11 Aug 2008 12:49:43 GMT

I'm with Trapalon -- I wouldn't touch this with ten foot pole, unless I had a serious medical issue. It seems like the kind of thing that could get FDA approved, and then we find out twenty years later that it's causing cancer.
But anyway, is this really different from anabolic steroids or hGH? This doesn't seem like a fundamentally new concept...

Getting buff without the sweat is cheating

Garrett, Troy NY — Mon, 11 Aug 2008 17:11:13 GMT

Take some accountability for your own actions, or lack there of. Our culture is not making us obese. Sure what other people around you do contribute to your own habits, but blaming your own faults on society doesn't solve anything. If you ask me the answer to obesity should be along the lines of better health care and education instead of taking a pill to mask the real problem. Providing a pill will only lead to abuse. I would be willing to bet that there will be some adverse side effects in humans with a drug of this nature. You just don't get drastic benefits like this without some kind of price.

Getting buff without the sweat is cheating

Dan Behar, Massapequa Park, NY — Mon, 11 Aug 2008 17:54:51 GMT

This definitely seems like a mixed blessing. On one hand, as many of you have stated, there are those who are physically unable to exercise, and this would be amazing for them. I can't imagine that this would be at all afordable for normal non prescription use, so hopefully it won't become a reason not to exercise. What I'm most surprised about in these replies though, is people's dislike for the act of exercising. I've recently started running more and adding a little bit of core training, and after doing it I simply feel amazing. Sure, it is a little bit of an inconvenience and popping a pill would be so much easier, but to me nothing beats the feeling of pushing yourself, accomplishing a physical goal and feeling so much natural energy pumping through your body.

Getting buff without the sweat is cheating

Gayle Longoria, San Antonio, Texas — Mon, 11 Aug 2008 23:02:52 GMT

The phrase "If it seems too good to be true, it probably is." comes to mind here.

Getting buff without the sweat is cheating

Michalchik, Newport Beach, California — Tue, 12 Aug 2008 19:23:31 GMT

This really pisses me off. First we invent fire, now this. In my day people kept themselves warm with furs and huddling together. That was good enough and it taught us how to skin an animal and kept us close as a tribe. It is good enough to me and should be good enough for you!

If these pills become popular people might not spend hours paying through the nose to mindlessly sweat while they move lumps of metal back and forth. It might give them time to play sports, hang out with their kids, further their career, invent a cure for cancer - It will be anarchy I tell you! Not to mention the it will turn the natural order on its head, this society deserves to be ruled by big steroid filled lunk-heads, now people who exercise their brains might look good too. And who will we have to look down on and laugh at if there are no fat weaklings.

I tell you this is the worst thing to happen since fire!

Getting buff without the sweat is cheating

Ken — Tue, 12 Aug 2008 20:33:28 GMT

"One pill makes you larger and one pill makes you small..." YIKES.

Getting buff without the sweat is cheating

Jesse, Portland, Oregon — Thu, 21 Aug 2008 11:30:15 GMT

Hear hear Michalchik!

I find it rediculous that so many of the posters automatically assume that anyone interested in the benefits of this (other than those with illness) has to be a fat, LAZY, couch potatoe. No way could there be a person who works 80+ hours a week (like the article says!) trying to manage home life and work life. Many people have demanding jobs that require little to no strenuous physical activity, i.e. the kind that builds your physique. Engineers, Surgeons, Anyone in the IT field, Teachers, the list go on. . .

Not saying a pill is the answer to everything, just don't be so presumptuous.

Getting buff without the sweat is cheating

Adam, San Diego, California — Thu, 21 Aug 2008 20:37:02 GMT

This is just the next phase in human evolution. We would be able to have the perverbial cake and eat it too. Imagine, humanity that is both fit and intelligent. I know that sounds like a certain Austrian megalomaniac, but if it gets our most intelligent scientists a fit body that will further positive procreation, why not? Maybe the next generation will be the first to realize that MTV doesn't play music anymore

Getting buff without the sweat is cheating

Mike — Thu, 21 Aug 2008 21:52:19 GMT

Give it to me... I'll gladly try it.
I WANT to be fit, trim and in shape.

Getting buff without the sweat is cheating

Genevieve, Little Rock, AR — Thu, 21 Aug 2008 21:54:00 GMT

As long as the pill's only given to people who can't exercise--like my mother, who's disabled--then I'm all for it. But if it's for people who just don't like exercise, or have horrible endurance and whatnot (which can easily be fixed with regular exercise) then it's not right. I can't help but wonder: with all these magic products and pills and operations, one of these days everyone's going to be completely gorgeous--then nobody will be. Will being ugly be the new pretty?

Getting buff without the sweat is cheating

Caitlin, Virginia — Fri, 22 Aug 2008 02:59:09 GMT

Please, people. The destination doesn't matter, just the journey? True, to an extent, but you can definitely take it too far. Saying you shouldn't take this pill because exersize builds character is like saying we shouldn't use word processors because hand printing things builds character, or shouldn't drive cars because walking builds character, or a host of other things. Would handwriting be a lot nicer if we didn't have word processors and typewriters? Yes, it would still be the borderline art form it was back in our grandparents' time. Is it a shame that it isn't still that way? Yes, it is. Is it enough of a shame that I would give up my copy of MS Word? Heck, no! Technology is a double-edged sword, it takes things away even as it improves lives. That doesn't mean we should stop our march forward, though

Getting buff without the sweat is cheating

Ram G., Scottsdale, AZ — Fri, 22 Aug 2008 05:04:41 GMT

As someone who exercises regularly, I think this has the potential to be excellent. Yes, it may be an "easy way out", but those of us who continue to exercise because of the psychological benefits (more serotonin and dopamine production for instance) will still be better off. I see it in the same vein as whey protein or creatine, though of course, much more extreme. Without exercise it still has the potential to produce results, but add exercise into the mix, and the results nearly double.

Getting buff without the sweat is cheating

Lara, Richland, Washington — Fri, 22 Aug 2008 15:34:47 GMT

I have diabetes and high cholesterol and a permanently screwed-with metabolism caused by a medication I take to keep me from either going manic or falling into deep depression. I also have exercise induced asthma, so I can't even do vigorous exercise. If a pill like that became available and didn't have any significant side effects (claims which I'd be very skeptical of, since I was also told that the drug that gave me all these problems now was a really, really good option), I'd take it in a heartbeat. I don't need to have sharply-defined muscles and rippling abs. I'd just be happy to get some weight off and not have to worry about a heart attack at age 35.

Getting buff without the sweat is cheating

Drew; Greensboro, N. Carolina — Mon, 25 Aug 2008 22:01:16 GMT

If this drug has no advers side effects, then it would be excellent for people suffering with degenerative muscle disease. However I have several issues with what people have said here:

1) If you have arthritis or bone spurs or some other disability that causes you pain when you move, this isn't going to help you at all. You'll have more muscle mass/endurance, but moving is still going to be painful. This drug doesn't affect your joints, bones, nerves, or anything else like that. If you can't run, or even bend over, will more muscle/endurance really help you?

2)For those of you looking to use this to improve your health (whether you really don't have the time to exercise or you're just plain lazy), again, all this is going to do is increase your muscle quality and quantity. It's not going to de-clog your arteries of cholesterol deposits or keep you from getting diabetes from the pounds of sugar you consume. As mentioned above, it may help you reduce your body fat because extra muscle requires extra energy to operate, but it really won't make up for a lack of nutrition. And if your body doesn't like to burn off fat during exercise, this probably won't help you either.

Furthermore, the building blocks for these extra muscle cells have to come from the food you eat. So your body's going to have a much tougher time making muscle if all you're eating is twinkies and pizza. This is not a substitute for proper nutrition.

3) How is this different functionally from steroids? Isn't that basically what they do? Isn't anyone wondering if these mice will suffer adverse side effects??? I didn't see anything about that in the report.

Getting buff without the sweat is cheating

Deric, Philly — Wed, 27 Aug 2008 20:43:02 GMT

Another pill to prolong millions of lazy peoples' lives? Forget it. I'm so sick of this pharma society. They're just drug dealers that pay taxes.
Can't sleep? Take this
Can't get an erection? Take this
Sad? Take this
Pain? Take this
Overweight? Take this

I'm absolutely positive the side effects will turn out to be disastrous.
"For every action, there is an equal,and opposite reaction"

Getting buff without the sweat is cheating

hammonton — Wed, 27 Aug 2008 20:44:24 GMT

Yes, Drew, you are right, you should try to exercise and eat properly to loose weight, however, what is the answer for people who are significantly overweight where any exersize can be life treatening? If a drug can help someone get over that exercise hump and maximize their results. Too many times people try to loose weight and exercise and get discouraged by some injury.

Getting buff without the sweat is cheating

DJ, Houston, Tx — Thu, 28 Aug 2008 12:05:41 GMT

I'm 60 years old. I work 10 hours a day and take care of a disabled spouse in the evenings. Exercise is a luxury I just don't have time for. A pill that could substitute for it might increase both my lifespan and my enjoyment of life. Bring it on!

Getting buff without the sweat is cheating

Flynnarrel, SF, CA — Thu, 28 Aug 2008 17:41:53 GMT

I'm surprised the military hasn't clamped down on this research and kept it from public so as to exclusively create better soldiers.

Getting buff without the sweat is cheating

Tama Buenker, T-town, Illinois — Thu, 18 Sep 2008 20:26:35 GMT

The story has no ending. What side effects are the mice suffering now? Steroids have their usefulness but we are now finding out the nasty things that happen to people who abuse them. There is always a flip side. If you are capable of doing it without drugs introduced into your system you will be better off in the long run.

Getting buff without the sweat is cheating

Jeremy, Brookly New York — Thu, 18 Sep 2008 21:48:10 GMT

Good lord... I can't believe some of the comments. Some of you are actually saying that this would be a BAD thing? Are you out of your mind?

I am all for anything that improves human beings. Frankly, our propensity to take "the easy way out" is exactly what allows us to invent all sorts of things. If necessity is the mother of invention laziness is surely its father. Why use a car... too lazy to walk? Why use a motor... too lazy to row? Get off your high horses people. If it works then use it.

I am way more interested in the brain enhancers... that is something many of the commentors here could sorely use. Wise up or shut up!

Getting buff without the sweat is cheating

Kai, Abilene TX — Sat, 20 Sep 2008 19:49:39 GMT

I see alot of issues coming from body builders and the endorphin junkies complaining about cheating. How many of you take supplemental pills/drinks to increase your muscular endurance or to build extra lean muscle mass faster? I would think all of you have your little shakes and pills. You do have gold cards at GNC for a reason don't you? How is this that much different? Extra effects for smaller effort, just like suppliments. Seems just as fair.

Getting buff without the sweat is cheating

Sarah, Two Rivers, AK — Wed, 08 Oct 2008 21:47:56 GMT

Haven't you two ever seen The Secret of NIMH?? God damn prophetic movie, I tell you what!

Getting buff without the sweat is cheating

Remy Austin TX — Fri, 07 Nov 2008 22:46:22 GMT

I used to be a marathon runner, but after a severe viral infection two years ago, I now I get sick every time I exercise. I feel faint and dizzy and clammy for hours, with circles under my eyes. I don't have a treatable condition, I'm just broken in a way medicine doesn't understand.

I would be interested in exploring this option.

Getting buff without the sweat is cheating

Eric, Allenstown NH — Fri, 02 Jan 2009 17:35:55 GMT

Wow.
A pill to work out.
Score 1 for the lazy guy!
I'll be first in line.
BUT...
if it works without side effects, makes you healthier, able to lead a more productive life without withering as fast, who cares.

The only real objection out there is from people who work out every day, run miles and miles, and sweat an hour or two of their day away. "But...but...I work out! This is cheating! WAAAAAAAHHHHHH!!!!"

Pills will replace everything sooner or later. Working out, eating, sex, all of it will be in pill-form.

That's not cheating, people. That's giving up.

Getting buff without the sweat is cheating

Marc, Baltimore MD — Sun, 01 Mar 2009 01:49:20 GMT

I'm a 22 year old full time college student that works two jobs just to barely stay afloat. I am without a doubt, extremely busy, yet I've never had a problem finding time to work out. When my peers are out on a Friday night partying, I'm hitting the pavement in my running shoes. I'm one of the few that actually enjoy working out. I like the fatigue that creeps up my calves when I hit the wall at mile 22, the burn in my quads when I cycle up that last 500 ft climb of the day, and all the little mental battles that I fight through to keep going, no matter how much I want to stop. I appreciate the act of pushing myself mentally and physically. Maybe you could call me an endorphin junky, but I think that's a poor way of describing it.

I'm an endurance athlete, and my training gives me so much more than just fitness. Only 3 years ago I was an unemployed drug addict with no desire to live. When I finally made the decision to help myself, exercise became a large part of my recovery. For the first time in my life I have energy, motivation, confidence and mental stability. Exercise is a large part of why I'm still alive. I don't think its fair to call me vain. I'm so much less concerned with how my body looks and so much more concerned with what my body can do. You're not inferior to me if you can't run a marathon. Physical prowess is not my criteria for determining the value of a human being. It's likely that there is something you can do far better than me.

As for the so-called negative effects of exercise, I've found that if you try to be smart about it, learn to listen to your body, work a well rounded routine and maintain a balance without pushing it to the extreme, more than likely you won't get injured. For the individuals capable of exercising, there is no good excuse not to. If you're not happy with your body or your energy level, do something about it. I wouldn't imagine a medication is going to substantially change the habits of anyone. The only realistic problem I could foresee is when relatively healthy, capable people begin to use it as a crutch.

I recognize however that many people are incapable of exercising at all or without experiencing extreme pain. I also recognize that I am more the exception than the rule. What I find to be the beauty in this medication is that the benefits of exercise still exist. A pill can't replace what I gain from my training. However, for individuals with developmental disabilities, degenerative muscle diseases or chronic pain, this medication is invaluable. If it can improve the standard of living for millions of people, there is no way any truly empathetic person could be against its use.

Healthcare costs are outrageous. The amount of money our society would save as a whole is unimaginable. The lesser strain on the system, the fewer cases of chronic and deadly diseases, a healthier population would decrease costs for everybody. Even if you disagree with the premise of the medication on face value, at least be comforted in knowing that it will probably save you money in the long run in addition to improving the lives of many. Longer life expectancies and fewer deaths aren't really a concern in the developed world anymore. In fact the United States is the only country in the G8 whose population is still growing (and that growth is stagnating quickly).

I agree that it would be in the best interest of everyone to be very thorough with pre-market research and prudent with its initial use. At the end of the day, if the medication proves to be safe and effective for humans, I will once again be astounded by the advancements of modern medicine.

Getting buff without the sweat is cheating

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