Allergic to exercise?

Posted on Wednesday, July 16, 2008 3:32 PM PT
Filed Under:

By Melissa Dahl

Does all that exertion on the elliptical machine make you nauseous? Have you ever been convinced that if you spend even one more minute on the treadmill, you will actually die? Maybe it’s not all in your head.

A few people are actually allergic to exercise, and in very rare cases, a sweaty workout could be enough to kill them.


Exercise-induced anaphylaxis is a fairly rare condition which can cause hives, fainting, vomiting and difficulty breathing during a workout, and the symptoms can last up to four hours after it. In some cases, it can be triggered by certain foods eaten before exercise, like peanuts, shellfish, eggs or even, in two reported cases, celery. But this isn't just your average food allergy, an expert explains.

"These are people who will not have this reaction unless they exercise right after eating this food," says Dr. Jacqueline Eghrari-Sabet, an allergist in private practice in Montgomery Village, Md., and a spokeswoman for the American Academy of Allergy, Asthma and Immunology. "Eating shellfish and sitting there? Nothing. But eating shellfish and exercising? For these people, it's bad news."

As you exercise and your heart rate speeds up, your blood starts whizzing through organs much faster, and therefore more frequently, than it normally does. With every trip your blood takes to your stomach, it's picking up more, say, celery bits. For those with exercise-induced anaphylaxis, the normal amount of celery antigens picked up by the blood isn't enough to bother them. But while exercising, the extra celery bits their blood is picking up causes an allergic reaction.

Running and jogging are the most likely to trigger an attack, but other strenuous activities like dancing, volleyball, skiing and even yard work can also cause a reaction.

Since the 1970s, only 1,000 cases of exercise-induced anaphylaxis have been documented – and among those cases, one death. Experts believe that’s because many people with this condition are able to recognize the symptoms quickly and keep it under control by waiting a couple hours after they eat to work out and bookending their workouts with a slow warm-up and cool-down.

"It'll usually happen when you're really exercising," says Eghrari-Sabet. "I don't think you're going to get it when you're bowling. But if you're doing cardio or a hip hop class, then, yes."

Others suffer from the less serious exercise allergy cholinergic urticaria, a common type of heat rash, which differs from anaphylaxis in that it starts and ends with the skin reaction – no nausea or difficulty breathing for these folks. Ten to 20 percent of the population will experience some form of it during their lives. Besides exercise, sun exposure, spicy foods or even getting too emotionally worked up can cause an itch attack.

The condition can strike spontaneously, so even if you’ve been exercising all your life with nary a rash, you can unexpectedly break out in hives. Even some marathon runners have suddenly come down with a bad case of the itches after jogging, explains Eghrari-Sabet. Women are most susceptible to the condition, and the average age for its first appearance is 16. (A handy way to get out of gym class?)

Unfortunately for people seeking an excuse not to break a sweat, most dermatologists and allergists send their patients with exercise-related allergies right back to the locker room.

“If they come to me, I’m not going to tell them not to exercise,” says Dr. Bruce Robinson, a Manhattan dermatologist.  Instead he advises patients to pick a less strenuous regimen or a cooler place to work out.

Because the itchy sensation happens when body temperature suddenly rises, it can be eased by warming up and cooling down slowly, before and after every workout. Or try swimming for your normal cardio routine, which will keep the body temperature cool. If a food allergy is the culprit, don’t eat for a couple of hours before your workout.

Although serious side effects are rare, some experts believe, that exercise-induced anaphylaxis often goes undiagnosed. So if you start to feel itchy while working out, watch out. It’s probably best to avoid death by treadmill at all costs.

For more on exercise allergies and other workout quandries, read our Smart Fitness column.

Comments

I have this too- my trigger food is wheat.  I broke out in hives at my wedding when I did the chicken dance after dinner.  How sad is that?  I keep zyrtec with me now and wait a good 2-3 hours to exercise if I've eaten anything wheat-related.  This article validates what I've experienced for the past 10 years.
I was diagnosed with cholinergic urticaria after breaking out in hives 2 or 3 times in the same year after a run.  The doc had me keep track of my eating habits and although it has only happened 3 more times (in a year and a half) since then, there is no correlation between what I have eaten (or even when) and having an episode.  Outside temperature, time of year... it's all random.  The ONLY thing we can point to is that it happens more when my seasonal allergies are active.  Usually a Benadryl fixes the problem and there are no lasting effects.
Most of the people who have experienced this allergy seem to be people who regularly exercise.  So, those being judgmental and accusing those who have this allergy of being lazy are just plain wrong.  I did not read many posts citing this being the reason they do not exercise.  Many commented they have experienced these symptoms and sought treatment of one kind or another so they could continue exercising.  I have absolutely experienced the itching on my legs and now regularly take my allergy medicine. Also, my face does get extremely red and intense workouts have caused my rosacea to flare up.  I have had that treated and continue to exercise.    
A little over six  (6) years ago I went on the exercising bike when I broke out with hives on my body from my calves up to my face. Since then it always bothered me. When my body gets heated or I go out in the sun a lot they show up, but if I go in a cool place they disappear. My doctor in New York was never able to see it because his room was always cold. I have seen a dermatologist hear in Indianapolis who prescribed 25Mg Hydroxyzine MCL but I never took in the day because it causes me to get drowsy at work. I have seen another dermatologist who put me on cyproheptadine 4Mg.
This is helping somewhat but itis bloating my stomach. It also makes me drowsy but I only take it when the hives show up. At times I just take one half of the tablet. I doesn't bother me that much. I have been wearing long or three quarter sleeves just to keep the sun off my skin. The times it shows up are when I am stressed, am in a hurry, or when my body gets heated. If the surroundings are cool I am fine. So far the doctor cannot say what is the source of my condition. Walking exercise is Ok for me.
Jean, Indianapolis, IN (Friday, July 18, 2008 5:00pm)
I wish those naysayers were right but if I were looking for an excuse not to exercise, this is not the one I would pick. I could use that one, too, if I truly wanted to. If EIA sufferers didn't exercise, we obviously wouldn't have the problem.  I didn't read where one person who says here they have this says they have chosen not to work out because of it. Sounds like we have all found ways to manage it and still keep working out.  I've been working out since I was 15 years old.  I have a 16 year old son who also is in phenomenal physical shape (he's shown no sign of this allergy), I'm 38 and still run 5 miles a day or bike 15 miles, plus strength, core and flexibility train - AFTER having a partial colonectomy in 2003. To the uneducated and self-righteous who have called us lazy, I think I speak for the majority of EIA sufferers: Wanna race? :-)
For KellyK, TX: While I don't have this particular condition, I do have exercise induced asthma. Can't run more than about 100 yard before breathing is actually painful. Unfortunately no medication helps. Hopefully they'll find a cure someday.
KellyK, TX (Thursday, July 17, 2008 6:26 PM)

I have exactly the same thing.  However, I was scratch tested for allergies and found out I'm allergic to dairy, chocolate, and cola.  Since I greatly reduced these I've no longer had severe reactions.
I find it funny that people would actually post that we are "fat and lazy" because we found that we have a condition WHILE WORKING OUT. We would have never known about this condition if we had not exercised in the first place. Not only that, now that I know I have this problem, I can work out in a way my body accepts and now I'm in the best shape I've ever been in. I'm stronger, faster, more balanced and right where I need to be with my weight now that I know how to exercise properly and take medication to prevent another outbreak.
For those that just don't get it: May you never have to "get it". I wouldn't wish this upon my worst enemy, and right now, just the fact that you were willing to post hurtful and uneducated rants, you're pretty close to that criteria.
First, I must express that I can't believe how quickly people judge. Please think twice before doing that, in all circumstances.

I'm 36 years old and have been running for nearly 25 years. I've run several marathons, half marathons, 10-milers, 5Ks, and 10Ks. I had my first EIA incident in April of 2008.  Since then I've had three more, and I can't find a common link between them. I landed in the ER the 1st time it happened, but I'm too embarrassed to go there again. The ER doctor seemed adamant that it was due to my lotion or clothes softener or even "middle-aged psychological stress that women my age often experience", but this article and everyone's comments have really convinced me that it is most likely a case of EIA. It has manifested itself differently each time - hives on my face, neck, trunk, scalp, and legs; swollen and itchy hands and feet (to the point of feeling like I'm going to die, or so swollen I almost could not get the Benadryl out of the blister packs); hot, red, swollen, itchy ears. I've always atrtibuted my frequent post-run dizziness, nausea, stomach cramps, and diarrhea to running, but maybe those have always been signs of the EIA? Anyway, thanks to all for sharing your stories. So far the Benadryl works for me, but it does make me sleepy, too. I like to use that as a good excuse to take a nap and have people leave me in peace and quiet for a while :)
Wow, nice to know I'm not alone. I just graduated college after running 4 years of track and field in my 4th year of competing I found that suddenly I couldn't keep up with workouts. I started wheezing after long runs. I found out I had EIA I mangaed it with an inhalor just fine. I could still run a good 400 time and was in supurb condition. That next fall I started getting red spots on my hands randomly on days when I'd worked out in the morning. This quickly escalated to hives from head to ankle. I had them everywhere but my feet. Hair, face, legs, it was terrible. I had to stop basically all physical activity cause they had me on so many medications all I could do was eat and sleep. I managed to get it under control I cut all processed foods out of my diet and have begun to work out again. Thank god! Now I can lose the 20 lbs I put on from those horrible steroids. The only medications that have worked for me were allegra and zantac to stop the breakouts. I still have the breakouts occasionally but they are farther between and less severe and I'm working out as hard as ever. Hopefully this will give some people hope.

P.S. To all the people who say I'm fat and lazy or a hypochondriac. Large red welts that other people can see and are so bad they point out to you are not in your head. The fact that I gained 20 pounds and still fit into a normal body fat % and BMI probably means I'm not lazy.

The worst part was the mental anguish of not being able to partake in activities that I enjoyed and had become such a part of my life I was 21 when this first occured and all I could see was me becoming a fat lazy blob because I couldn't bust a sweat without making m body so sick it slept for two whole days. I'm only 23 now and I fell much better but it took 2 whole years and 20 lbs to figure out what worked for me. DON'T GIVE UP!!
WOW, this is a great article!  I'm in the military and as soon as I would get done running for PT, my legs would break out in debilitating, painful, itchy hives, so bad I would be in tears.  I switched to swimming in place of running and have not since had a problem, but I thought I was unique in this regard.  Great to know!
I just came home today, after having an episode that sounds like what everyone here is talking about. It's something I've noticed over the years but because I don't do aerobic activity on a regular basis, I just tossed it off as a quirky thing. But today, when I got home, there were welts all over my upper right thigh from all the scratching I must have done.

I was diagnosed with a rare lung disease a year and a half ago- Brochiolitis Obliterans and then 9 months later was diagnosed with Rheumatoid Arthritis. The BO and the RA are related.

I'm wondering if EIA is also related to any auto immune issues.  Just saying...

Glad to have found this site.
I have had severe itching from knees to waist with brisk walking since I was young.  It can proceed to nausea. I have never associated it with food, but I have noticed if I walk nearly every day, it is not a problem.  If I haven´t walked in some days, it comes back.  It seems that I desensitize myself if I walk every day.
Wow, this is really comforting!  I had my first problem when I was about 14 or 15.  I was walking around the mall with my mom and broke out into excruciatingly painful hives.  Mine however, isn't related to the food I eat.  I used to go running in the morning (before I ate breakfast) and would still break out.  My doctor diagnosed me with this condition.  Now I just take a Zyrtec every day to keep the allergy at bay.  It doesn't stop it completely, but it does allow me to still work out for quite a while.  I'm so glad I found this article, I feel like I'm not alone!
My Dad used to walk for 45mins in the morning unfortunatly he has relised his lips and one part of face has swelled suddenly... is this is ALLERGIC REACTION?
OK, let me repeat that… I like the way you react to my   somber  incentive  A JOKE! )   How can you have bread if you are on a liquid diet? Drink a toast!!   I want to have a good time, Lets speack about something people!
OMG! I am so exited to hear.  Now, I don't have towaste a co-pay to go to the doctor tomorrow.  For the last 22 years, my thighs would begin to itch, seems like, from the inside out.  Then they would turn red and itch on top of my skin.  The more I scratched, the more it itched.  In high school, my track coach would give me benadryl about 30 minutes before my races and that helped.  But now I work out at lunch and can't take Benadryl.  I will try claritin.
I've always been sensitive to heat, but as soon as I turned 15 I got hives whenever it got hot out. My gym teacher thinks I'm lazy when I say I can't participate in class, and he doesn't believe me when I say I get hives.
Then he made me run a mile for a fitness test, and when he saw my hive-encrusted arms, he finally understood. :]
I found that yoga is a nice alternative, if one still wants to work out with this condition.
I have had the itching thighs and legs since I was a child (or pre-teen) and was always told that it was my imagination, or "just my muscles working, work through the pain" but I actually started to want to avoid running and walking long distances, because of the horrible itching pain.  I have tried to track hot or cold wether, clothing, etc. but it seems random.  I am so glad to hear that I am not crazy.  I have eczema and other allergies too.


Send a comment

PLEASE READ: All comments must be approved before appearing in the thread; time and space constraints prevent all comments from appearing. We will only approve comments that are directly related to the blog, use appropriate language and are not attacking the comments of others.

Message (please, no HTML tags. Web addresses will be hyperlinked):

Your name, city and state (John Doe, Seattle, Wash.): 

Your e-mail address (jdoe@msnbc.com):

Your website (it's okay if you don't have one):

Remember me? (We'll keep it private)

About the blog

Insights and ruminations on the strangeness of all things medical, pharmaceutical and biological.

Msnbc.com writers and editors will muse upon the wonderfully weird human body and the medical curiosities that make you go huh, ewww or ouch! Looking for informed, unhinged meditations on everything from dubious diseases to recipes for ersatz mucous? Well, this is the place.

If you have a question, e-mail The Body Odd.

Archives


Add this blog to your news reader