Why do hangovers seem so much worse as we get older?

Chris Hondros / Getty Images

Revelers clink beer glasses and enjoy themselves during an all day party at historic McSorley's Old Ale House March 17, 2004, in New York.

Sometime tomorrow, around the time your alarm clock rings, you will hate yourself for trying to keep up with your college self this St. Patrick's Day. You used to be able to bounce right back from hangovers; now, if you have more than two pints of Guinness tonight you know you'll feel it in the morning. What happened?

It's not your imagination. Our bodies really do start to lose the capability to process booze as we get older, an alcohol expert explains.

"The critical enzymes for breaking down booze are somewhat diminished in efficiency as we age," says Jim Schaefer, an alcohol metabolism expert and an anthropology professor at Union College in Schenectady, N.Y. The enzymes your body depends on to break down booze are alcohol dehydrogenase, or ALDH, and aldehyde dehydrogenase, or ADH. Excuse the alphabet soup, but ALDH breaks down ethanol (booze) into acetaldehyde, and then ADH breaks down the acetaldehyde into a non-toxic substance called acetic acid. "It has been suggested that acetaldehyde is one of the key toxic chemicals that influences the severity of a hangover," Schaefer says. "So any deterioration in ADH levels would contribute to worse hangovers."

Whiskey sales boom lifts Irish spirits

Another reason not to chase your college years tonight: Cheaper booze also tends to intensify hangovers. Inexpensive beer, wine and liquor are more likely to have higher congener content -- congeners are the "chemical soup" that results from the fermentation or distillation process, Schaefer explains. "The more expensive liquors are often filtered and triple or more distilled -- thus, cleaner alcohol, less junk," he says.

"As we age, we may be unable to avoid chemical changes that could be wrecking the efficiency of our liver, and we should avoid lousy intoxicants, as they are guaranteed to cause digestive or metabolic discomfort," Schaefer adds.

Let's review: If you are past your college drinkin' days, don't throw back a bunch of green-tinted Miller High Lifes. If you must imbibe tonight, stick to the fancy stuff, and your pounding headache Friday morning will be at least a little less pound-y.

Do you feel your hangovers have gotten worse as you've aged? At what age did you notice it? Or, do you generally avoid drinking enough booze to cause a hangover?

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The solution is simple enough. As we grow older, most of us acquire experience and wisdom, no...?

  • 1 vote
#1 - Thu Mar 17, 2011 8:49 AM EDT

the solution is simpler....you can still have fun, just drink water before you go to bed

lots and lots of water

  • 9 votes
#1.1 - Thu Mar 17, 2011 9:25 AM EDT

A recent article suggested the best scientific cure for a hangover is coffee, before going to bed or a few hours after you've calmed down from drinking. The caffeine does something to increase the metabolism of acetaldehyde. It has worked wonders for me, and who shouldn't enjoy themselves with friends and a couple of drinks when they can? I'm too busy on weekends to see everyone, so I love being able to head to a bar on a weeknight and feel fine the next morning.

I may be biased though. I am young.

    #1.2 - Thu Mar 17, 2011 10:30 AM EDT

    take vitamin b and c, with a big glass of water, before you go to bed. alcohol strips vitamin b from your body, and vitamin c always helps.

    • 5 votes
    #1.3 - Thu Mar 17, 2011 10:49 AM EDT

    Not to add to the "I have the miracle cure" posts, but chemically, here you go...

    Drink a glass of milk before drinking. It coats your stomach.

    Drink Gatorade between each new can/bottle/shot. It replenishes lost electrolytes.

    Eat a banana right before bed. It counters the diuretic effect of alcohol and helps prevent dehydration and several trips to the bathroom overnight.

    Eat a few eggs in the morning. The cysteine counters hangover symptoms.

    If you can handle all that, you'll feel great.

    • 3 votes
    #1.4 - Thu Mar 17, 2011 12:26 PM EDT

    If I did all that I'd puke...LOL

    • 11 votes
    #1.5 - Thu Mar 17, 2011 1:15 PM EDT

    The perfect cure: take an ice cold shower in the morning. Figured that one out on spring break years ago. We would party all night and hit the beach the next morning, but the water was still very cold. All that adrenaline from the cold water knocks it out. It sucks while youre doing it, but you get out very refreshed and hang over free.

    • 1 vote
    #1.6 - Thu Mar 17, 2011 1:33 PM EDT

    I agree with MmmMmmBeer. Drink as much water as you can before going to bed - for me, it nips the hangover in the bud and I wake up feeling just fine. Its worth having to get up in the night to "go".

      #1.7 - Thu Mar 17, 2011 1:38 PM EDT

      I agree with Christine. Over the years I have learned what to drink, when, with who, how much, how often and for how long. A healthy life style, good food and exerscise also helps. Not much more to say.

        #1.8 - Thu Mar 17, 2011 1:40 PM EDT

        My hangovers have haunted me for over 40 years...never had much tolerance for alcohol..a couple of drinks or 6 I will still have the next day blues....once in awhile I get no hangover after a nite on the town...that is a rare blessing but keeps me trying to repeat the good morning after...I try to limit myself to two drinks but sometimes I slip into the Ray Malland character in " The Lost Weekend. "

          #1.9 - Thu Mar 17, 2011 2:34 PM EDT

          Yep, green tea works well too, i get the gallon jug of arizona. Lots of water the day before and some food the next morning and i am right as rain.

          Still taking Friday off though, hangover may not be a worry at 35, but sleep still is.

            #1.10 - Thu Mar 17, 2011 2:58 PM EDT

            Fast food and Gatorade works for me!

            A big, sloppy "Big N Tasty" from Burger King for brunch, followed by delivery Chinese food for dinner(hot and spicy soup, egg rolls, and Orange Beef) and a huge bowl of ice cream around 10 at night.

            I'm 32, but I exercise enough to where I can get away with that, for the most part...but this is a once or twice a month occurrence, unlike college which was party central From Wednesday night until Sunday morning.

              #1.11 - Thu Mar 17, 2011 3:07 PM EDT

              doyourhomework,America!

              take vitamin b and c, with a big glass of water, before you go to bed. alcohol strips vitamin b from your body, and vitamin c always helps.

              Learned about this in my home brewing guide. Vitamin C never hurts, but Vitamin B helps a lot. One of those "vitamin overdose" packs before you crash also helps quite a bit in keeping the hangover away.

                #1.12 - Thu Mar 17, 2011 3:27 PM EDT

                I've decided that one of the issues is tolerance. Usually slow and steady wins the race but not in the drinking games. When one is young, pounding the booze as quickly as possible till the money runs out works. When one is older, one has the finances to start earlier in the evening and go longer. More booze equals more ill effects.

                  #1.13 - Thu Mar 17, 2011 4:03 PM EDT

                  The only problem drinker is the one that never buys.

                  • 2 votes
                  #1.14 - Thu Mar 17, 2011 4:26 PM EDT

                  drink the high life tonight..........feel like a low life tommorow.

                  • 2 votes
                  #1.15 - Thu Mar 17, 2011 4:44 PM EDT

                  I also agree with the "drink a lot of water" comments. If that still doesn't work, a nice greasy breakfast with eggs and bacon and/or sausage will fix it up pretty quickly.

                    #1.16 - Thu Mar 17, 2011 4:47 PM EDT

                    A toke on good hash will make you forget that the earth rotates around MARS (sic) and you will have no memory of how you got to where you are - when you do wake up. Moreover, you will not care!

                    • 3 votes
                    #1.17 - Thu Mar 17, 2011 7:57 PM EDT

                    The hangovers do NOT get worse, but your poor old aging decrepit mind THINKS they do.

                      #1.18 - Fri Mar 18, 2011 6:27 AM EDT

                      It's simple, try to eat before you sleep if you can if not pop up aspirin before you sleep and drink a lot of energy drinks the following day to replenish lost electrolytes

                        #1.19 - Fri Mar 18, 2011 8:37 AM EDT

                        @ France

                        I used to pop aspirin before bed but my doctor told me it really destroys your kidneys something fierce, especially since you're not flushing your system with water since you are sleeping, the compounds just gestate in your kidneys

                          #1.20 - Fri Mar 18, 2011 9:53 AM EDT

                          if you live in canada, a gravol before bed and 2 extra strength ibuprofen works like a charm. just know you'll be brain dead the next day, so don't do if you have to work. and tylenol is not the way...its bad for the liver which is working overtime!

                            #1.21 - Sat Mar 19, 2011 9:13 PM EDT

                            I have not noticed my hangovers get worse over the past 35 years........cuz I never did drink, smoke or do drugs........ahahhahhhaaahahhhaaa!

                              #1.22 - Wed Dec 21, 2011 11:07 PM EST
                              Reply

                              I'm 50 now and drinking to excess hurts a lot more now than it used to. I had chalked it up to the fact I do not drink as often as I did in my 20s. I really started noticing it in my 40s.

                              • 4 votes
                              Reply#2 - Thu Mar 17, 2011 8:51 AM EDT

                              So, can those alphabet soup enzymes be synthesized and sold OTC in ingest-able form? If not. how about a patch or nasal spray?

                              • 1 vote
                              #2.1 - Thu Mar 17, 2011 1:39 PM EDT

                              That is brilliant. Why hasn't anyone done that? I would buy it.

                              • 1 vote
                              #2.2 - Thu Mar 17, 2011 2:34 PM EDT

                              yeeaah, just what we need is more pills to throw our bodies out of whack...

                                #2.3 - Thu Mar 17, 2011 3:49 PM EDT
                                Reply

                                I never had a hangover until I turned 21. Aint life grand?

                                  Reply#3 - Thu Mar 17, 2011 8:52 AM EDT

                                  Same here, and they've steadily gotten worse since. Some days I can actually 'see' my pulse in my vision, when I've really had my finest hour the night before.

                                  • 3 votes
                                  #3.1 - Thu Mar 17, 2011 9:45 AM EDT

                                  welcome to the real world. now sit down and drink your beer.

                                  • 4 votes
                                  #3.2 - Thu Mar 17, 2011 10:50 AM EDT

                                  When I was in my clubbing days (18-25) I could kill a 18 pack, a pint of vodka, and a few 40s b4 I fell asleep. And still get up at 8 shower and go work a full 8 hour day then start right up that evening. Im 28 now and really slowed down on the party scean (got faded on wine one night, ouch). Now I can handle one night of binging but spend the next day in discomfort. I will say I can still go 3 days in a row, but leave me alone the entire next week. I drink water and eat b4 I go to bed now, and cold Monster ready in the AM, nvr on a work night tho. They talk about tolerance, back then beer hurt more than liqure, now it reversed.

                                    #3.3 - Thu Mar 17, 2011 11:27 AM EDT
                                    Reply

                                    Never had a hangover til I was in my 30s. One was enough, I never drink enough to be hung over now.

                                    • 4 votes
                                    Reply#4 - Thu Mar 17, 2011 8:53 AM EDT

                                    In my mind I'm still 21, but in reality I'm 43! I work long hours, live in a man camp, in a country where alcohol is illegal. Of course when I take holiday every 10 to 12 weeks, it doesn't take long before the party begins. I'm pretty good about stopping myself before I become legless, but holy cow the hangovers last for days! I need a cure for this? anyone?

                                      Reply#5 - Thu Mar 17, 2011 8:55 AM EDT

                                      Of course, the most common approach to not getting a hangover, is to simply not drink. But for those that do, the most effective way to prevent, or at least reduce the threat, is to drink an equal amount of water..... so as to dilute the alcohol in the blood stream. Wish I had known that when I was younger !!!!!!! LOL!!

                                      • 2 votes
                                      Reply#6 - Thu Mar 17, 2011 9:00 AM EDT

                                      I don't think hangovers have become worse for me. The reality is that, in college, I had nothing better to do on a Saturday morning than sleep in to recover. However, now, I have multiple things I would rather do (or have to do) and, therefore, can't afford to hibernate in a dark room all day.

                                        Reply#7 - Thu Mar 17, 2011 9:00 AM EDT

                                        I agree.... I had hangovers in college, I was just able to sleep and lazy them off. Now I have to get up, go to meetings, go to the gym, run errands, etc.... you feel it more when you have thing to do that require that your brain and body are sharp.

                                          #7.1 - Thu Mar 17, 2011 10:51 AM EDT

                                          Just remember... No brain, no headache!

                                            #7.2 - Tue Mar 22, 2011 6:53 PM EDT
                                            Reply

                                            A hangover is natures way of telling you, you should have smoked pot.

                                            • 38 votes
                                            Reply#8 - Thu Mar 17, 2011 9:01 AM EDT

                                            Agreed ^_^ and if you use a vaporizor, you eliminate most of the bad stuff! Let's get pot legal in the U.S.A. in the next 10 years, and tax it. Anyone arguing it's worse than alcohol in any way is a brainwashed moron, being led around like a sheep.

                                            • 6 votes
                                            #8.1 - Thu Mar 17, 2011 10:07 AM EDT

                                            Indeed!!

                                            • 2 votes
                                            #8.2 - Thu Mar 17, 2011 10:53 AM EDT

                                            everyone with netflix go watch "The Union"

                                              #8.3 - Thu Mar 17, 2011 11:57 AM EDT

                                              except... alcohol makes you want to socialize, dance, and flirt. That's why it's so popular. Pot makes you want to eat and watch a movie at home. Fine for a Tuesday but that makes for one hell of a boring weekend.

                                                #8.4 - Thu Mar 17, 2011 3:38 PM EDT

                                                Do vaporizers prevent the burning, hacking coughing???? That is the downside for me.

                                                • 1 vote
                                                #8.5 - Thu Mar 17, 2011 5:03 PM EDT
                                                Reply

                                                The reason people get hangovers is because they dont drink enough. If your going to go out on St Patricks Day and hang one on you have to go out a couple times before that. You have to keep a little booze in your system so it isnt such a shock when you do tip them back. Drinking upscale booze does help also. Elementary my dear Watson.

                                                • 3 votes
                                                Reply#9 - Thu Mar 17, 2011 9:09 AM EDT

                                                Just keep drinking.

                                                • 5 votes
                                                Reply#10 - Thu Mar 17, 2011 9:10 AM EDT

                                                At 41, I *definitely* notice this effect. Wine in particular really hurts the next day. I'm glad to read that this 'aging effect' isnt in my mind.

                                                • 2 votes
                                                Reply#11 - Thu Mar 17, 2011 9:12 AM EDT

                                                Im young and wine still hurts very much badly in the mornings >.< ugh

                                                  #11.1 - Thu Mar 17, 2011 5:10 PM EDT
                                                  Reply

                                                  DRINK - VOMIT - SLEEP :)

                                                  • 1 vote
                                                  Reply#12 - Thu Mar 17, 2011 9:15 AM EDT

                                                  Yes, hangovers, though they don't happen often, are worse.  What I notice is the fog that stays with me throughout the entire next day.  I just can't think straight.  The other thing I've noticed in about the last 4 years (I'm 43), is sometimes when I drink (seems to happen more with beer or wine) is I wake up in the middle of the night with my heart POUNDING, like it's going to burst out of my chest.  It's a horrible feeling.  I don't even have to drink much at all- it can be one glass of wine or one beer.  And it doesn't always happen.  It's the strangest thing ever and really bums me out...

                                                    Reply#13 - Thu Mar 17, 2011 9:16 AM EDT

                                                    The SAME thing happens to me!!! Heart pounds away like crazy. I take 1/2 a Benadryl before bed and sleep right through it now. Dont have to do often as I dont drink like I used to.

                                                      #13.1 - Thu Mar 17, 2011 10:51 AM EDT

                                                      Same thing happens to me, but it happened once during the middle of the day after a few nights of staying up late and drinking. Really freaked me out, thought I was having a heart attack. Embarrassing and scary at the same time. Freaks me out when I drink too much now thinking it might happen again.

                                                        #13.2 - Thu Mar 17, 2011 11:53 AM EDT

                                                        Hi CJ,

                                                        I'm a physician near 50 and I've tried to scientifically figure out what you describe (as it is a terrible feeling!). The heart pounding is from the acetaldehyde, a temporary breakdown product in the metabolism of alcohol. Acetaldehyde is a poison, a known carcinogen. The liver is supposed to break it down quickly. It can cause esophageal or other cancers over time. Knowing what I now know about the whole process scares me so much that I rarely drink more than a glass of wine these days!

                                                          #13.3 - Thu Mar 17, 2011 11:58 AM EDT

                                                          Check your blood pressure. I used to get that after a couple of beers too. Once I got that under control it's not nearly as bad. It might even be mild withdrawl.

                                                            #13.4 - Thu Mar 17, 2011 4:59 PM EDT

                                                            Wow - interesting! That happens to me, too, and I am always a little freaked out by it. Glad to hear I'm not the only one!

                                                            And yeah, I definitely limit when and how much I drink now vs. what I used to. If it's a weeknight, that means only a glass, maybe two if it's early. Anything more has to wait til the weekend, when I have a whole day to recover if I need it!

                                                            And don't even get me started on the weight gain drinking causes later in life - that really sucks!

                                                              #13.5 - Thu Mar 17, 2011 5:02 PM EDT
                                                              Reply

                                                              Somewhere in my late 20's/early 30's hangovers started getting more acute, for some reason Corona beer gives me the worst headaches, maybe its the crappy water from south of the border?

                                                              • 1 vote
                                                              Reply#14 - Thu Mar 17, 2011 9:20 AM EDT

                                                              I don't drink Corona because of the horrible hangovers plus it taste like skunk.

                                                                #14.1 - Thu Mar 17, 2011 4:47 PM EDT
                                                                Reply

                                                                Way worse now than even just 5 years ago. I feel so bad the next day, I rarely drink at all now. I feel like I got hit by a truck even with just a few beers, and I drink the good import dark beers that are expensive. My body is telling me "turn out the lights, the party's over!" My liver sent me a thank you card and gift basket.

                                                                  Reply#15 - Thu Mar 17, 2011 9:20 AM EDT

                                                                  Aaaaaand the hangovers hurt more than they used to... and cornbread and iced tea took the place of pills and 90 proof

                                                                    Reply#16 - Thu Mar 17, 2011 9:23 AM EDT

                                                                    And thus the reason I never allow myself to get sober

                                                                    • 6 votes
                                                                    Reply#17 - Thu Mar 17, 2011 9:28 AM EDT

                                                                    I think its due to the ingredients changing over the past few years. It would be interesting to know what sort of genetically modified bits there are in today's beer along with concentrates.

                                                                    An Alka-Seltzer before you to bed and one when you wake up is my trick. Doesn't work much anymore though....

                                                                    How about listing the ingredients on the bottle like all other food!!

                                                                      Reply#18 - Thu Mar 17, 2011 9:35 AM EDT

                                                                      It's on the bottle you drunk! Though the older we get the more difficult it is to read the small print. Get the cheaters out and have a beer.

                                                                        #18.1 - Tue Mar 22, 2011 7:04 PM EDT
                                                                        Reply

                                                                        I had read that if you drink, eat a bunch of slices of cucumber before going to bed you won't have a hangover. I tried it and it works. There is always cucumber in my frig and liquor in my cabinet! haha

                                                                          Reply#19 - Thu Mar 17, 2011 9:40 AM EDT

                                                                          Yes; also if you steep cucumber slices in a pitcher of water and use that as a mixer you can really get away with it!

                                                                            #19.1 - Thu Mar 17, 2011 10:23 AM EDT
                                                                            Reply

                                                                            Now I know the facts........as the economy tanked I went back to "college wine" screw on caps and the hang overs got worst. I will be glad when the economy improves and I am able to go back to the more refined stuff.

                                                                              Reply#20 - Thu Mar 17, 2011 9:47 AM EDT

                                                                              Without going into a treatise on organic chemistry, acetaldehyde is basically embalming fluid. The chemical difference between formaldehyde and acetaldehyde is one carbon atom. Antabuse works on this principle. It stops the metabolism of alcohol at acetaldehyde and as such you are basically embaliming yourself. Dehydration also plays a role in a hangover. Alcohol inhibits production of Antidiuretic hormone which is partly why you pee a lot when you drink. As such your electrolytes become depleted which is one reason your muscles feel achy. Being in the medical field, when I would over serve myself, I found drinking a liter of Lactated Ringer's prevented a hangover nicely. Not getting @!$%# faced prevents a hangover even better

                                                                              • 1 vote
                                                                              Reply#21 - Thu Mar 17, 2011 9:56 AM EDT

                                                                              Embalming fluid........... huh ....... No wonder at 48 I look so young. I always just thought i was pickeled! LOL

                                                                              • 2 votes
                                                                              #21.1 - Thu Mar 17, 2011 1:46 PM EDT
                                                                              Reply

                                                                              Its Obama's fault....

                                                                              Lots of great wines have screw of tops now....do some research...has nothing to do with "college wine"

                                                                                Reply#22 - Thu Mar 17, 2011 9:58 AM EDT

                                                                                Yeah, everything is his fault. FYI "great" wines do not have screw on caps now because of Obama. Crap wine/ bottom of the barrel/ and basic table wines do. Its called truth in packaging. It protects consumers by not allowing companies to decieve them into thinking they are actually drinking Burgandy for $2.50. You are still free to buy those sub par wines, and believe me they havnt got any worse with screw on caps. But youre right, hangovers are Obama's fault.

                                                                                  #22.1 - Thu Mar 17, 2011 2:52 PM EDT
                                                                                  Reply

                                                                                  if theres a dairy queen on one corner and a liquior store on the other corner ill go for the ice cream everytime now

                                                                                    Reply#23 - Thu Mar 17, 2011 10:03 AM EDT

                                                                                    A hangover is nature's way of bitchslapping you for your complete and utter stupidity. That's the simple bottom line.

                                                                                    • 1 vote
                                                                                    Reply#24 - Thu Mar 17, 2011 10:04 AM EDT

                                                                                    it's also nature's way of saying you did a lot of living last night.

                                                                                    hangovers be damned- party on!

                                                                                    • 4 votes
                                                                                    #24.1 - Thu Mar 17, 2011 10:54 AM EDT
                                                                                    Reply

                                                                                    As my husband says 'Cheap white wine will do it every time.' and it does it every time to me, i know that. If I stick to the good stuff, i am much better off. I have also learned to never mix the grain and the grape, and to avoid gin at all costs. I really resent all the time I have to waste getting over a stupid hangover, so try to drink loads of water before going to bed and having something in my stomach before drinking. But I still love a good wine , a tasty beer or a sharp and salty marguerita sitting in the sun. I'll be dead a long time, I know that!

                                                                                    • 1 vote
                                                                                    Reply#25 - Thu Mar 17, 2011 10:06 AM EDT

                                                                                    i have learned to avoid vodka at all costs. ugh. dumb russian alchohol.

                                                                                      #25.1 - Thu Mar 17, 2011 5:18 PM EDT
                                                                                      Reply
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